GANT58 for cell activation

GANT58 for cell activation is available 2 times from Biovision labs

1812-5 | GANT58 for cell activationsize: 5 mg | 180.07 USD

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1812-25 | GANT58 for cell activationsize: 25 mg | 526.07 USD

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  • Description
    Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC₅₀ ~ 5 µM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and antitumor activity in vivo.
  • Peptide sequence
    N/A
  • CAS number
    64048-12-0
  • Molecular weight
    392.48
  • Category
    Biochemicals
  • Molecular formula
    C₂₄H₁₆N₄S
  • Physical appearance
    Yellow solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (25 mM) or Ethanol (25 mM)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    GANT58 for activation
  • Technique
    activation
  • Alternative name
    GANT58 to measure cellular activation
  • Tissue
    cell
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