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GALR1 Antibody Conjugated

GALR1 Antibody Conjugated is available 8 times from Bioss primary conjugated antibodies labs

bs-9927R-Biotin | GALR1 Antibody, Biotin Conjugated size: 0.1ml | 381.95 USD

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bs-9927R-Cy3 | GALR1 Antibody, Cy3 Conjugated size: 0.1ml | 401.45 USD

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bs-9927R-Cy5 | GALR1 Antibody, Cy5 Conjugated size: 0.1ml | 401.45 USD

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bs-9927R-Cy5.5 | GALR1 Antibody, Cy5.5 Conjugated size: 0.1ml | 401.45 USD

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bs-9927R-Cy7 | GALR1 Antibody, Cy7 Conjugated size: 0.1ml | 401.45 USD

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bs-9927R-FITC | GALR1 Antibody, FITC Conjugated size: 0.1ml | 381.95 USD

Long name GALR1 Polyclonal Antibody, FITC Conjugated
Conjugation FITC
Tested applications FCM, IF(IHC-P)
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200)
Storage conditions Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission 494nm/518nm
Properties If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
Additional conjugation Anti-FITC Antibody
French translation anticorps
Gene targetGALR1 Conjugated
Short name GALR1 Antibody, FITC Conjugated
Technique Antibody, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
Label FITC
Alternative name GALR1 (Antibody to), fluorecein coupled
1. Gene info
Identity4132
GeneGALR1
Long gene name galanin receptor 1
Synonyms gene
GenBank acession
Locus18q23
Discovery year 1994-12-19
Entrez gene record2587
Pubmed identfication
Classification
  • Galanin receptors
Havana BLAST/BLATOTTHUMG00000132875
MeSH Data
Concept
Scope note:Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
Additional information
PubMedGalanin, acting via the GAL1 receptor and Gi -coupled signalling in L and K cells, is a potent inhibitor of GLP-1 and GIP secretion
excess GAL in cognitive impairment is relevant to the overexpression of GAL in the basal forebrain during the progression of Alzheimer's disease
Homozygous Galr1-/- mice are viable, capable of breeding, and exhibit no significant difference in growth rate. They have reduced circulating levels of insulin-like growth factor-I (IGF-I) and exhibit spontaneous tonic-clonic seizures.
GAL-R1 knockout mice are unimpaired on a number of tests of learning and memory with the exception of the trace version of cued fear conditioning.
GalR1 knockout mice showed no difference with respect to acute nociception, but showed a modest tendency towards increased hyperalgesia after tissue injury and inflammation
GALR1 deficiency impaired adaptation to a 3-day high-fat diet challenge, leading to increased food intake, feed efficiency and weight gain.
differential expression of Galr1 may contribute to the differences in susceptibility to seizure-induced cell death between cell death-resistant and cell death-susceptible strains
In GalR1KO mice, a high dose of galanin failed to induce any of the above effects, suggesting the pivotal role of GalR1 in decreased locomotor activity and stress-resistant effects caused by galanin i.c.v. injection studied here.
Rotavirus infection of murine small intestine causes colonic secretion via age restricted galanin-1 receptor expression.
Experiments with a GalR1-preffering galanin analog, NAX-5055, show that GalR1 is involved in regulating glucose and insulin homeostasis
Entrez Genegalanin receptor 1  (GALR1)

bs-9927R-HRP | GALR1 Antibody, HRP Conjugated size: 0.1ml | 401.45 USD

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bs-9927R-PE | GALR1 Antibody, PE Conjugated size: 0.1ml | 422.1 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen GALR1
Specificity This is a highly specific antibody against GALR1.
Modification Unmodified
Modification site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Subcellular location Extracellular
Source KLH conjugated synthetic peptide derived from human GALR1
Gene ID number 2587
Crossreactivity Human
Crossreactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background GALR1 is a G-protein-coupled receptor for the neuropeptide galanin that influences endocrine secretions, intestinal motility, memory, weight, and pain perception. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, and in peripheral sites such as the small intestine and heart. The rat galanin receptor cDNA cloned from an insulinoma cell line is a predicted 346-amino acid G protein-coupled receptor with 92% homology to the human GALR1.
Purification method This antibody was purified via Protein A.
Synonyms GAL1R; galanin receptor 1; Galanin receptor; Galanin receptor type 1; GALNR; GALNR1; GALR1; GALR1_HUMAN.
Alternative technique antibodies
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