GABRB2/GABA A Receptor beta 2 Antibody, Cy5 Conjugated

• Catalog number
  bs-12065R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  GABRB2/GABA A Receptor beta 2 Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GABRB2/GABA A Receptor beta 2
• Specificity
  This is a highly specific antibody against GABRB2/GABA A Receptor beta 2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human GABRB2/GABA A Receptor beta 2
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  GABA; GABAA receptor subunit beta-2; GABRB2; Gamma aminobutyric acid GABA A receptor, beta 2; Gamma aminobutyric acid A receptor beta 2; Gamma-aminobutyric acid receptor subunit beta-2; Gamma-aminobutyric-acid receptor subunit beta-2; GBRB2_HUMAN,
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  GABRB2/GABA   Receptor   beta   Conjugated  
• Gene symbol
  GABRB2, ABAT
• Short name
  Anti-GABRB2/GABA A Receptor beta 2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-GABRB2/GABA A Receptor beta 2 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4082
• Gene
  GABRB2
• Long gene name
  gamma-aminobutyric acid type A receptor subunit beta2
• Synonyms gene name
  • gamma-aminobutyric acid (GABA) A receptor, beta 2
• Synonyms name
  • GABA(A) receptor, beta 2
• Locus
  5q34
• Discovery year
  1994-04-29
• Pubmed identfication
  • 7851879
• Classification
  • Gamma-aminobutyric acid type A receptor subunits
• VEGA ID
  OTTHUMG00000130349

Gene info

• Identity
  HGNC:23
• Gene
  ABAT
• Long gene name
  4-aminobutyrate aminotransferase
• Synonyms
  • GABAT
  • GABA-T
• Synonyms name
  • 4-aminobutyrate transaminase
  • gamma-aminobutyrate aminotransferase
  • GABA transaminase
• GenBank acession
  • L32961
• Locus
  16p13.2
• Discovery year
  1996-03-13
• Entrez gene record
  18
• Pubmed identfication
  • 7721088
• RefSeq identity
  • NM_020686
• VEGA ID
  OTTHUMG00000048201

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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