GAB2 (Tyr452) Antibody

• Catalog number
  bs-3178R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GAB2 (Tyr452) Primary Polyclonal Antibody
• Also known as
  GAB2 (Tyr452) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GAB2 Tyr452
• Specificity
  This is a highly specific antibody against GAB2 Tyr452.
• Modification s
  Phosphorylation
• Modification site s
  Tyr452
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  430-470/676
• Source
  KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Tyr452
• Gene ID number
  9846
• Swiss Prot
  Q9UQC2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp1; GAB2; KIAA571
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GAB2   Tyr452  
• Gene symbol
  GAB2
• Short name
  Anti-GAB2 Tyr452
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GAB2 (Tyr452) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  GRB2-associated binding protein 2, GAB2 and IDBG-65975 and ENSG00000033327 and 9846, phosphatidylinositol-3, Plasma membranes

Gene info

• Identity
  HGNC:14458
• Gene
  GAB2
• Long gene name
  GRB2 associated binding protein 2
• Synonyms
  • KIAA0571
• Synonyms name
  • Grb2-associated binder 2
• GenBank acession
  • AB011143
• Locus
  11q14.1
• Discovery year
  2001-01-24
• Entrez gene record
  9846
• Pubmed identfication
  • 10391903
  • 10068651
• RefSeq identity
  • NM_080491
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000166673

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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