Collagen Type VIII Rabbit Polyclonal

Products_type

Antibody
Products_short_name

[Collagen Type VIII]
Other_names

[collagen, type VIII, alpha 2; Collagen alpha-2(VIII) chain; collagen alpha-2(VIII) chain; collagen type VIII alpha 2; Endothelial collagen]
Other_gene_names

[COL8A2; COL8A2; FECD; PPCD; FECD1; PPCD2]
Clonality

Polyclonal
Reactivity

Human, Mouse, Rat
Purity

>=95% as determined by SDS-PAGE Immunogen Affinity Purified
Form

Liquid
Storage_stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Tested_application

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Gene

Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name

Oryctolagus cuniculus

Gene target

Collagen VIII
Gene symbol

COX8A, G3BP1, MARCHF8
Short name

Collagen VIII Rabbit Polyclonal
Technique

Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Rabbit, Rabbits
Isotype

IgG
Alternative name

Collagen classification VIII production species: rabbit polyclonal
Alternative technique

polyclonals, rabbit-anti

Identity

HGNC:2294
Gene

COX8A
Long gene name

cytochrome c oxidase subunit 8A
Synonyms gene
- COX8
Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
Synonyms
- COX8-2
- COX8L
- VIII-L
- COX
- VIII
GenBank acession
- J04823
Locus

11q13.1
Discovery year

1989-06-30
Entrez gene record

1351
Pubmed identfication
- 2543673
- 2847943
- 26685157
RefSeq identity
- NM_004074
Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
VEGA ID

OTTHUMG00000167785

Identity

HGNC:30292
Gene

G3BP1
Long gene name

G3BP stress granule assembly factor 1
Synonyms gene name
- GTPase activating protein (SH3 domain) binding protein 1
Synonyms
- HDH-VIII
- G3BP
Synonyms name
- Ras-GTPase-activating protein SH3-domain-binding protein
- DNA helicase VIII
GenBank acession
- BC006997
Locus

5q33.1
Discovery year

2006-10-25
Entrez gene record

10146
Pubmed identfication
- 8649363
- 9889278
- 25229650
RefSeq identity
- NM_005754
Classification
- RNA binding motif containing
- Endoribonucleases
VEGA ID

OTTHUMG00000130123

Identity

HGNC:23356
Gene

MARCHF8
Long gene name

membrane associated ring-CH-type finger 8
Synonyms gene
- MIR
- MARCH8
Synonyms gene name
- c-mir, cellular modulator of immune recognition
- membrane-associated ring finger (C3HC4) 8
- membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Synonyms
- c-MIR
- CMIR
- MARCH-VIII
- RNF178
GenBank acession
- AL833316
Locus

10q11.21-q11.22
Discovery year

2003-11-12
Entrez gene record

220972
Pubmed identfication
- 12582153
- 14722266
RefSeq identity
- NM_145021
Classification
- Ring finger proteins
- Membrane associated ring-CH-type fingers
VEGA ID

OTTHUMG00000019345