CDH1 (813CT11.1.3) Monoclonal Antibody
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Catalog number
bsm-51214M
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Price
Please ask
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Size
0.1ml
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Long name
CDH1 (813CT11.1.3) Monoclonal Antibody
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Also known as
CDH1 (813CT11.1.3) Monoclonal Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
CDH1
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Specificity
This is a highly specific antibody against CDH1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Monoclonal
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Clone number
813CT11.1.3
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Source
Purified His-tagged CDH1 protein was used to produced this monoclonal antibody.
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Gene ID number
999
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Swiss Prot
P12830
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Tested Applications
WB, IHC-P
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Recommended dilutions
IHC-P(1:25), WB(1:1000),
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Cross reactivity
Human, Mouse
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
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Purification method
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
CDH1, FZR1
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Short name
Anti-CDH1
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Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Host
Mouse (Mus musculus)
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Isotype
Immunoglobulin G (IgG)1 κ
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Alternative name
CDH1 (813CT11.1.3) Monoclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
cadherin 1, type 1, E-cadherin (epithelial), Arc-1 and CD324 and CDHE and ECAD and LCAM and UVO, CDH1 and IDBG-38622 and ENSG00000039068 and 999, cell adhesion molecule binding, Extracellular, Cdh1 and IDBG-190074 and ENSMUSG00000000303 and 12550, BT.64827 and IDBG-634263 and ENSBTAG00000015991 and 282637
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Gene info
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Identity
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Gene
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Long gene name
cadherin 1
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Synonyms gene
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Synonyms gene name
- cadherin 1, type 1, E-cadherin (epithelial)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Type I classical cadherins
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VEGA ID
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Locus Specific Databases
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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