FLT3, phosphorylated (Tyr591) (FL Cytokine Receptor, Fms-like Tyrosine Kinase 3, FLT-3, Stem Cell Tyrosine Kinase 1, STK-1, Tyrosine-protein Kinase Receptor FLT3, CD135, STK1)[FLT3]

• Catalog number
  MBS630926
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  For cells, cell lines and tissues in culture till half confluency. Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Test
  Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.

• Gene target
  FLT3   phosphorylated   Tyr591   Cytokine   Receptor   Fms-like   Tyrosine   Kinase   FLT-3   Stem   Tyrosine   Kinase   STK-1   Tyrosine-protein   Kinase   Receptor   FLT3   CD135   STK1   [FLT3]  
• Gene symbol
  FLT3, CDK7, FLT1, YWHAZ, TRR-ACG1-3, TRF-GAA1-3, TRR-CCG1-3, MIR3130-1, TRW-CCA3-3, TRE-CTC1-3
• Short name
  FLT3, phosphorylated (Tyr591) (FL Cytokine Receptor, Fms-like Tyrosine Kinase 3, FLT-3, Stem Tyrosine Kinase 1, STK-1, Tyrosine-protein Kinase Receptor FLT3, CD135, STK1)[FLT3]
• Host
  Rabbit
• Alternative name
  fms-related tyrosine kinase 3, phosphorylated (Tyr591) (FL Cytokine Receptor, Fms-like Tyrosine phosphorylation catalyst 3, FLT-3, progenitor cellular Tyrosine phosphorylation catalyst 1, STK-1, Tyrosine-protein phosphorylation catalyst Receptor fms-related tyrosine kinase 3, CD135, STK1)[fms-related tyrosine kinase 3]
• Alternative to gene target
  fms-related tyrosine kinase 3, CD135 and FLK-2 and FLK2 and STK1, FLT3 and IDBG-19891 and ENSG00000122025 and 2322, transferase activity, nuclei, Flt3 and IDBG-209045 and ENSMUSG00000042817 and 14255, BT.28173 and IDBG-630678 and ENSBTAG00000018572 and 512700
• Tissue
  cell, stem

Gene info

• Identity
  HGNC:3765
• Gene
  FLT3
• Long gene name
  fms related receptor tyrosine kinase 3
• Synonyms gene name
  • fms-related tyrosine kinase 3
  • fms related tyrosine kinase 3
• Synonyms
  • STK1
  • FLK2
  • CD135
• GenBank acession
  • U02687
• Locus
  13q12.2
• Discovery year
  1990-07-30
• Entrez gene record
  2322
• Pubmed identfication
  • 8394751
• Classification
  • Immunoglobulin like domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000016646
• Locus Specific Databases
  • LRG_457

Gene info

• Identity
  HGNC:1778
• Gene
  CDK7
• Long gene name
  cyclin dependent kinase 7
• Synonyms gene name
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
• Synonyms
  • CAK1
  • CDKN7
  • MO15
  • STK1
  • CAK
• Locus
  5q13.2
• Discovery year
  1994-12-16
• Entrez gene record
  1022
• Pubmed identfication
  • 8069918
• RefSeq identity
  • NM_001799
• Classification
  • Cyclin dependent kinases
  • CDK activating kinase complex
• VEGA ID
  OTTHUMG00000099358

Gene info

• Identity
  HGNC:3763
• Gene
  FLT1
• Long gene name
  fms related receptor tyrosine kinase 1
• Synonyms gene
  • FLT
• Synonyms gene name
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • fms-related tyrosine kinase 1
  • fms related tyrosine kinase 1
• Synonyms
  • VEGFR1
• Synonyms name
  • vascular endothelial growth factor receptor 1
  • vascular permeability factor receptor
• GenBank acession
  • AF063657
• Locus
  13q12.3
• Discovery year
  1986-01-01
• Entrez gene record
  2321
• Pubmed identfication
  • 2158038
• RefSeq identity
  • NM_002019
• Classification
  • Receptor tyrosine kinases
  • I-set domain containing
• VEGA ID
  OTTHUMG00000016648
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_425

Gene info

• Identity
  HGNC:12855
• Gene
  YWHAZ
• Long gene name
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
• Synonyms gene
  • YWHAD
• Synonyms gene name
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
• Synonyms
  • KCIP-1
  • 14-3-3-zeta
• Synonyms name
  • 14-3-3 zeta
  • 14-3-3 delta
• GenBank acession
  • U28964
• Locus
  8q22.3
• Discovery year
  1993-09-20
• Entrez gene record
  7534
• Pubmed identfication
  • 8617504
  • 7890696
• RefSeq identity
  • NM_145690
• Classification
  • 14-3-3 phospho-serine/phospho-threonine binding proteins
• VEGA ID
  OTTHUMG00000134291

Gene info

• Identity
  HGNC:34806
• Gene
  TRR-ACG1-3
• Long gene name
  tRNA-Arg (anticodon ACG) 1-3
• Synonyms gene
  • TRNAR21
  • TRR-ACG1-1
• Synonyms gene name
  • transfer RNA arginine 21 (anticodon ACG)
  • transfer RNA-Arg (ACG) 1-1
  • transfer RNA-Arg (ACG) 1-3
• Synonyms
  • tRNA-Arg-ACG-1-3
• GenBank acession
  • HG983594
• Locus
  14q11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189243
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34984
• Gene
  TRF-GAA1-3
• Long gene name
  tRNA-Phe (anticodon GAA) 1-3
• Synonyms gene
  • TRNAF11
  • TRF-GAA1-1
• Synonyms gene name
  • transfer RNA phenylalanine 11 (anticodon GAA)
  • transfer RNA-Phe (GAA) 1-1
  • transfer RNA-Phe (GAA) 1-3
• Synonyms
  • tRNA-Phe-GAA-1-3
• GenBank acession
  • HG983960
• Locus
  11q12.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189415
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34735
• Gene
  TRR-CCG1-3
• Long gene name
  tRNA-Arg (anticodon CCG) 1-3
• Synonyms gene
  • TRNAR19
  • TRR-CCG1-1
• Synonyms gene name
  • transfer RNA arginine 19 (anticodon CCG)
  • transfer RNA-Arg (CCG) 1-1
  • transfer RNA-Arg (CCG) 1-3
• Synonyms
  • tRNA-Arg-CCG-1-3
• GenBank acession
  • HG983601
• Locus
  16p13.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189173
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:38275
• Gene
  MIR3130-1
• Long gene name
  microRNA 3130-1
• Synonyms gene
  • MIR3130-3
• Synonyms gene name
  • microRNA 3130-3
• Synonyms
  • hsa-mir-3130-1
  • hsa-mir-3130-3
• Locus
  2q33.3
• Discovery year
  2010-04-30
• Entrez gene record
  100422993
• RefSeq identity
  • NR_036077
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:34674
• Gene
  TRW-CCA3-3
• Long gene name
  tRNA-Trp (anticodon CCA) 3-3
• Synonyms gene
  • TRNAW3
  • TRW-CCA3-1
• Synonyms gene name
  • transfer RNA tryptophan 3 (anticodon CCA)
  • transfer RNA-Trp (CCA) 3-1
  • transfer RNA-Trp (CCA) 3-3
• Synonyms
  • tRNA-Trp-CCA-3-3
• GenBank acession
  • HG984066
• Locus
  17p13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189112
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34953
• Gene
  TRE-CTC1-3
• Long gene name
  tRNA-Glu (anticodon CTC) 1-3
• Synonyms gene
  • TRNAE22
• Synonyms gene name
  • transfer RNA glutamic acid 22 (anticodon CUC)
  • transfer RNA-Glu (CTC) 1-3
• Synonyms
  • tRNA-Glu-CTC-1-3
• GenBank acession
  • HG983755
• Locus
  1q23.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189385
• Classification
  • Cytoplasmic transfer RNAs

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