FKBP25 Antibody
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Catalog numberbs-13178R
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PricePlease ask
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Size0.1ml
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Long nameFKBP25 Primary Polyclonal Antibody
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Also known asFKBP25 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenFKBP25
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SpecificityThis is a highly specific antibody against FKBP25.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP25
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Gene ID number2287
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenFKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesFKBP 25; FKBP 3; FKBP25; FKBP3; PPIase; Rotamase; FKBP3_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolFKBP3
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Short nameAnti-FKBP25
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameFKBP25 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameFKBP prolyl isomerase 3
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Synonyms gene name
- FK506-binding protein 3 (25kD)
- FK506 binding protein 3, 25kDa
- FK506 binding protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-09-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- FKBP prolyl isomerases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data