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Target antigen
Filensin
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Clonality
Monoclonal antibody
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Clone
FIL-7B10
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Raised in
mice
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Type of the antibody
IgG1 monoclonal antibody
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Product form
freeze-dried
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Reacts with species
Human, bovine
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Analyses
WB,IHC-F
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Immunogen
Human and bovine lens filament enriched fraction(plasma membrane-cytoskeleton complex).
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Product configuration
Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
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Purification
Ascites
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Solubilization
The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
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Storage condtions
Keep the Filensin Antibody ( FIL7B10)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Filensin Antibody ( FIL7B10) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Filensin, also known as beaded filament structure protein 1, have two major component BFSP1 and BESP2. Filensin gene is mapped at 20p12.1-p11.23. The sequence of the predicted 665-amino acid human protein is 62% and 50% identical to those of bovine and chicken filensin, respectively. However, it has less than 26% identity to other members of the intermediate filament(IF) family.
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Related articles
1. Rendtorff, N. D.; Hansen, C.; Silahtaroglu, A.; Henriksen, K. F.; Tommerup, N. : Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1. Genomics 53: 114-116, 1998. 2. Hess, J. F.; Casselman, J. T.; FitzGerald, P. G. : Chromosomal locations of the genes for the beaded filament proteins CP 115 and CP 47. Curr. Eye Res. 14: 11-18, 1995.
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Gene Name
BFSP1
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Protein Name
Filensin
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Gene Full Name
beaded filament structural protein 1, filensin
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Synonyms
CP115|CP94|CP115|LIFL-H|LIFL-H CYTOSKELETAL PROTEIN, 115-KD|Beaded filament structural protein 1|Lens fiber cell beaded-filament structural protein CP 115|Lens intermediate filament-like heavy
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Uniprot ID
Human(Q12934), Mouse(A2AMT1), Rat(Q02435)
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Entrez GeneID
Human(631), Mouse(12075), Rat(25394)
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
