FIIN 2 for cell activation

FIIN 2 for cell activation is available 2 times from Biovision labs

9577-25 | FIIN-2 for cell activationsize: 25 mg | 735.84 USD

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9577-5 | FIIN-2 for cell activationsize: 5 mg | 229.37 USD

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  • Description
    FIIN-2 is a potent, selective, irreversible, next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547.
  • Peptide sequence
    N/A
  • CAS number
    1633044-56-0
  • Molecular weight
    634.73
  • Category
    Biochemicals
  • Other name
    N-(4-((3-(3,5-dimethoxyphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide
  • Molecular formula
    C₃₅H₃₈N₈O₄
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO >6 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    FIIN-2 for activation
  • Technique
    activation
  • Alternative name
    FIIN-2 to measure cellular activation
  • Tissue
    cell
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