Fibulin 2 Antibody

• Catalog number
  bs-13160R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Fibulin 2 Primary Polyclonal Antibody
• Also known as
  Fibulin 2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Fibulin 2
• Specificity
  This is a highly specific antibody against Fibulin 2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibulin 2
• Gene ID number
  2199
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Fibulin-2; Fbln2; FBLN2_HUMAN; FIBL-2; Fibulin-2; OTTHUMP00000216670; OTTHUMP00000216671; OTTHUMP00000216672.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Fibulin  
• Gene symbol
  EFEMP2, FBLN2
• Short name
  Anti-Fibulin 2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Fibulin 2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3219
• Gene
  EFEMP2
• Long gene name
  EGF containing fibulin extracellular matrix protein 2
• Synonyms gene name
  • EGF-containing fibulin-like extracellular matrix protein 2
  • EGF containing fibulin like extracellular matrix protein 2
• Synonyms
  • FBLN4
  • UPH1
• Synonyms name
  • fibulin 4
• GenBank acession
  • AF109121
• Locus
  11q13.1
• Discovery year
  2000-03-01
• Entrez gene record
  30008
• Pubmed identfication
  • 10601734
  • 10982184
• RefSeq identity
  • NM_016938
• Classification
  • Fibulins
• VEGA ID
  OTTHUMG00000166664

Gene info

• Identity
  HGNC:3601
• Gene
  FBLN2
• Long gene name
  fibulin 2
• GenBank acession
  • X82494
• Locus
  3p25.1
• Discovery year
  1994-02-24
• Entrez gene record
  2199
• Pubmed identfication
  • 7806230
• RefSeq identity
  • NM_001004019
• Classification
  • Fibulins
• VEGA ID
  OTTHUMG00000155437

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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