FGFR2 Antibody

• Catalog number
  R30343
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  FGFR2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the FGFR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This FGFR2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P21802
• Purity
  Antigen affinity
• Description
  Fibroblast growth factor receptor 2(FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.
• Immunogen
  An amino acid sequence from the N-terminus of human FGFR2 (EYLQIKGATPRDSGLYACTA) was used as the immunogen for this FGFR2 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the FGFR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FGFR2  
• Gene symbol
  FGFR2
• Short name
  Anti-FGFR2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to FGFR2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3689
• Gene
  FGFR2
• Long gene name
  fibroblast growth factor receptor 2
• Synonyms gene
  • KGFR
  • BEK
  • CFD1
  • JWS
• Synonyms gene name
  • bacteria-expressed kinase
  • keratinocyte growth factor receptor
  • craniofacial dysostosis 1
  • Jackson-Weiss syndrome
• Synonyms
  • CEK3
  • TK14
  • TK25
  • ECT1
  • K-SAM
  • CD332
• Synonyms name
  • Crouzon syndrome
  • Pfeiffer syndrome
• GenBank acession
  • AK026508
• Locus
  10q26.13
• Discovery year
  1991-05-09
• Entrez gene record
  2263
• RefSeq identity
  • NM_022976
  • NM_000141
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000019175
• Locus Specific Databases
  • LRG_994

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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