FGF14, human recombinant

• Catalog number
  7347-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27
• Alternative_names
  Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27
• Description
  Involved in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Molecular Weight
  30.0 kDa (271 aa, 1-247 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  0.25 mg/ml
• Appearance
  Liquid
• Physical form description
  0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 5 mM DTT and 50% glycerol.
• Background Information
  FGF14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. Recombinant human FGF14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MGSHMAAAIA SGLIRQKRQA REQHWDRPSA SRRRSSPSKN RGLCNGNLVD IFSKVRIFGL KKRRLRRQDP QLKGIVTRLY CRQGYYLQMH PDGALDGTKD DSTNSTLFNL IPVGLRVVAI QGVKTGLYIA MNGEGYLYPS ELFTPECKFK ESVFENYYVI YSSMLYRQQE SGRAWFLGLN KEGQAMKGNR VKKTKPAAHF LPKPLEVAMY REPSLHDVGE TVPKPGVTPS KSTSASAIMN GGKPVNKSKT T
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  FGF14  
• Gene symbol
  FGF14-AS1, FGF14-IT1, FGF14-AS2, FGF14
• Short name
  FGF14, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  FGF14, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:40237
• Gene
  FGF14-AS1
• Long gene name
  FGF14 antisense RNA 1
• Synonyms gene name
  • FGF14 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AI217925
• Locus
  13q33.1
• Discovery year
  2011-05-18
• Entrez gene record
  100874081
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000017302

Gene info

• Identity
  HGNC:42774
• Gene
  FGF14-IT1
• Long gene name
  FGF14 intronic transcript 1
• Synonyms gene name
  • FGF14 intronic transcript 1 (non-protein coding)
• Locus
  13q33.1
• Discovery year
  2011-08-18
• Entrez gene record
  283480
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000017301

Gene info

• Identity
  HGNC:44368
• Gene
  FGF14-AS2
• Long gene name
  FGF14 antisense RNA 2
• GenBank acession
  • BC033993
  • BM674599
  • BX096285
• Locus
  13q33.1
• Discovery year
  2012-09-12
• Entrez gene record
  283481
• Pubmed identfication
  • 26820525
• RefSeq identity
  • NR_036487
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000185723

Gene info

• Identity
  HGNC:3671
• Gene
  FGF14
• Long gene name
  fibroblast growth factor 14
• Synonyms
  • FHF4
  • SCA27
• Locus
  13q33.1
• Discovery year
  1996-12-18
• Entrez gene record
  2259
• Pubmed identfication
  • 8790420
  • 17236779
• Classification
  • MicroRNA protein coding host genes
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000017303

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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