FASP1 Antibody

• Catalog number
  bs-9738R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FASP1 Primary Polyclonal Antibody
• Also known as
  FASP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FASP1
• Specificity
  This is a highly specific antibody against FASP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FASP1/C21orf45
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  B28; C21orf46; FASP1; hMis18alpha; MaFF interacting protein; MAFIP; MIS18A; Protein Mis18 alpha; MS18A_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FASP1  
• Gene symbol
  MIS18A
• Short name
  Anti-FASP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FASP1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1286
• Gene
  MIS18A
• Long gene name
  MIS18 kinetochore protein A
• Synonyms gene
  • C21orf46
  • C21orf45
• Synonyms gene name
  • chromosome 21 open reading frame 46
  • chromosome 21 open reading frame 45
  • MIS18 kinetochore protein homolog A (S. pombe)
• Synonyms
  • B28
  • FASP1
  • hMis18alpha
• GenBank acession
  • AF231921
• Locus
  21q22.11
• Discovery year
  2000-05-23
• Entrez gene record
  54069
• Pubmed identfication
  • 17199038
• RefSeq identity
  • NM_018944
• VEGA ID
  OTTHUMG00000085308

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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