FASL Monoclonal Antibody [H11], FITC Conjugated

• Catalog number
  A-0523-100
• Price
  Please ask
• Size
  0,1 ml

• Target antigen
  FASL
• Clone
  H11
• Conjugation additive
  FITC Conjugated
• Product type
  Antibody
• Clonality
  monoclonal antibody
• Long name
  FASL Monoclonal Antibodies [H11], FITC Conjugated
• Description
  This item is a monoclonal antibody against FASL. Monoclonal antibodies ensure a highly specific binding to a certain epitope of the antigen and are much more LOT-to-LOT consistent than polyclonal antibodies.
• Storage conditions
  For short term storage the FASL Monoclonal Antibody [H11], FITC Conjugated can be kept refrigerated at +4 degrees Celsius. For long term storage keep frozen at -20 degrees Celsius. Be sure to refer to the technical sheet for any additional specifications and requirements for proper storing of the antibodies.
• Tips
  FASL MAb [H11], FITC Conjugated should not be exposed to cycles of freezing and thawing as they may denaturate the peptide chains/bonds in the antibodies and reduce/change the activity of the antibody. Prior to use briefly centrifuge the vial to collect its content on the bottom.
• Properties
  If you buy Antibodies supplied by Epigen they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Epigen Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Epigen FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  FASL   Monoclonal   [H11]   Conjugated  
• Gene symbol
  FASLG, HSPB8
• Short name
  Anti-FASL
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein, Monoclonals or monoclonal antibodies
• Label
  FITC
• Alternative name
  FASL MAb [H11], FITC Conjugated
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:11936
• Gene
  FASLG
• Long gene name
  Fas ligand
• Synonyms gene
  • APT1LG1
  • TNFSF6
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 6
  • Fas ligand (TNF superfamily, member 6)
• Synonyms
  • FasL
  • CD178
• GenBank acession
  • U11821
• Locus
  1q24.3
• Discovery year
  1994-12-09
• Entrez gene record
  356
• Pubmed identfication
  • 7826947
  • 9022072
• Classification
  • Tumor necrosis factor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000034841
• Locus Specific Databases
  • FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base)
  • LRG_58

Gene info

• Identity
  HGNC:30171
• Gene
  HSPB8
• Long gene name
  heat shock protein family B (small) member 8
• Synonyms gene name
  • heat shock 27kDa protein 8
  • heat shock 22kDa protein 8
• Synonyms
  • H11
  • E2IG1
  • HSP22
  • CMT2L
• GenBank acession
  • AF191017
• Locus
  12q24.23
• Discovery year
  2004-01-29
• Entrez gene record
  26353
• Pubmed identfication
  • 10833516
  • 11085516
• RefSeq identity
  • NM_014365
• Classification
  • Small heat shock proteins
• VEGA ID
  OTTHUMG00000168932
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_249

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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