anti-human FAS ligand (FasL) monoclonal antibody

• Catalog number
  MBS468025
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [FASL]
• Products_name_syn
  [CD95; Fas ligand]
• Other_names
  [tumor necrosis factor ligand superfamily member 6; tumor necrosis factor ligand superfamily member 6; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; Fas ligand (TNF superfamily, member 6); Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL]
• Other_gene_names
  [FASLG; FASLG; APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; APT1LG1; CD95L; FASL; TNFSF6; APTL; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA]
• Clonality
  Monoclonal
• Clone
  [GM-5F4]
• Reactivity
  Human
• Specificity
  anti-human Fas ligand (FasL)
• Purity
  Protein G
• Form
  Purified
• Storage_stability
  Short term: 2 degree C - 8 degree C; long term: -20 degree C (avoid repeated freezing and thawing)
• Tested_application
  Flow Cytometry (FC/FACS)and CELISA
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  MyBioSource supplies antibodies that are for research of human proteins.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  FAS   ligand   FasL   monoclonal  
• Gene symbol
  FAS-AS1, FASN, FAS
• Short name
  anti- FAS ligand (FasL) monoclonal antibody
• Technique
  anti-Human, Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, Monoclonals or monoclonal antibodies
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans
• Alternative name
  Antibody tohuman Fas (tumor necrosis factor receptor superfamily, member 6) ligand (FasL) monoclonal (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488

Gene info

• Identity
  HGNC:37128
• Gene
  FAS-AS1
• Long gene name
  FAS antisense RNA 1
• Synonyms gene
  • FASAS
  • FAS-AS
• Synonyms gene name
  • FAS antisense RNA (non-protein coding)
  • FAS antisense RNA 1 (non-protein coding)
• Synonyms
  • SAF
• Locus
  10q23.31
• Discovery year
  2009-07-16
• Entrez gene record
  100302740
• Pubmed identfication
  • 15829500
  • 24811343
  • 27141526
• RefSeq identity
  • NR_028371
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3594
• Gene
  FASN
• Long gene name
  fatty acid synthase
• Synonyms
  • FAS
  • SDR27X1
• Synonyms name
  • short chain dehydrogenase/reductase family 27X, member 1
• GenBank acession
  • U26644
• Locus
  17q25.3
• Discovery year
  1994-05-17
• Entrez gene record
  2194
• Pubmed identfication
  • 7835891
  • 7567999
  • 19027726
• RefSeq identity
  • NM_004104
• Classification
  • Short chain dehydrogenase/reductase superfamily
  • 7BS orphan methyltransferases
• VEGA ID
  OTTHUMG00000178527

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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