FAF1 Antibody

• Catalog number
  R30402
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  FAF1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the FAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This FAF1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9UNN5
• Purity
  Antigen affinity
• Description
  Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.
• Immunogen
  An amino acid sequence from the N-terminus of human FAF1 (MASNMDREMILADFQACTGIEN) was used as the immunogen for this FAF1 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the FAF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FAF1  
• Gene symbol
  FAF1-AS1, FAF1
• Short name
  Anti-FAF1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to FAF1
• Alternative technique
  antibodies
• Alternative to gene target
  Fas (TNFRSF6) associated factor 1, hFAF1 and HFAF1s and UBXD12 and UBXN3A, FAF1 and IDBG-98407 and ENSG00000185104 and 11124, NF-kappaB binding, nuclei, Faf1 and IDBG-174694 and ENSMUSG00000010517 and 14084, FAF1 and IDBG-639656 and ENSBTAG00000014482 and 531770

Gene info

• Identity
  HGNC:40228
• Gene
  FAF1-AS1
• Long gene name
  FAF1 antisense RNA 1
• Locus
  1p32.3
• Discovery year
  2019-07-25
• Entrez gene record
  105378715
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3578
• Gene
  FAF1
• Long gene name
  Fas associated factor 1
• Synonyms gene name
  • Fas (TNFRSF6) associated factor 1
• Synonyms
  • CGI-03
  • hFAF1
  • HFAF1s
  • UBXD12
  • UBXN3A
• Synonyms name
  • TNFRSF6-associated factor 1
  • UBX domain protein 3A
• GenBank acession
  • AF132938
• Locus
  1p32.3
• Discovery year
  1999-12-10
• Entrez gene record
  11124
• Pubmed identfication
  • 10462485
• RefSeq identity
  • NM_007051
• Classification
  • UBX domain containing
• VEGA ID
  OTTHUMG00000007930

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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