Factor XIIa Activity Assay Kit (Colorimetric)

• Catalog number
  K994-100
• Price
  Please ask
• Size
  100 assays

• Description
  Highly Sensitive, minimum sample preparation required
• Summary
  • Detection method- Colorimetric (Absorbance 405 nm) • Applications- Measurement of FXIIa activity in plasma and purified/crude enzyme preparations
• Detection Method
  Colorimetric (Absorbance 405 nm)
• Species Reactivity
  Mammalians
• Applications
  Measurement of Factor XIIa activity in plasma samples and purified/crude enzyme preparations
• Sample Type
  Plasma and Purified enzyme
• Features Benefits
  • Simple, rapid & convenient assay to measure Factor XIa • Includes Positive Control and Factor XIIa and Factor XIIa Inhibitors
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Factor XII or Hageman factor (EC 3.4.21.38), is the zymogen form of factor XIIa, a serine protease involved in Coagulation Pathway. This single chain zymogen is activated by Kallikrein into a two-chain serine protease (XIIa) with a heavy chain (factor XIIa-alpha) and a light chain. Human Factor XII and Prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates Prekallikrein to Kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. The defects in this gene do not cause any clinical symptoms but prolong the whole blood clotting time. BioVision's Factor XIIa activity assay kit utilizes the ability of factor XIIa to cleave a synthetic substrate to release p-Nitroaniline (pNA) which can be quantitatively measured by a colorimetric assay (OD405 nm). The kit is easy-to-use and can detect Factor XIIa (as low as 1 mPEU) from plasma sampless.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.
• Properties
  Colorimetric assays or detection use UV absorption or enzymatic color reaction.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  Factor   XIIa   Activity   Kit  
• Short name
  Factor XIIa Activity Assay Kit (Colorimetric)
• Technique
  colorimetric, Assay, assays, colorimetry
• Host
  Assay
• Alternative name
  Factor XIIa Activity test reagent (colorimetry)
• Alternative technique
  assays, arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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