EZSolution™ Nec-1s

• Catalog number
  2535-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione); 7-Cl-O-Nec-1
• Description
  A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (~100 mM). More useful for in-cell and in vivo experiments compared to Nec-1.
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₁₂ClN₃O₂
• Molecular Weight
  277.71
• Cell Permeable
  Yes
• Purity
  ≥96% by LC-MS
• Handling
  Protect from light and moisture
• Tag Line
  A potent necroptosis inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• PubChem CID
  643953
• PubChem CID Link
• SMILES
  CN1C(=O)C(NC1=O)CC2=CNC3=C2C=CC=C3Cl
• InChi
  InChI=1S/C13H12ClN3O2/c1-17-12(18)10(16-13(17)19)5-7-6-15-11-8(7)3-2-4-9(11)14/h2-4,6,10,15H,5H2,1H3,(H,16,19)
• InChi Key
  WIKGAEMMNQTUGL-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  EZSolution™   Nec-1s  
• Short name
  EZSolution™ Nec-1s
• Alternative name
  EZSolution™ Nec-1s

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