IL-13, rat recombinant
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Catalog number4166-10
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PricePlease ask
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Size10 ug
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SynonymsNC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.
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Alternative_namesNC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.
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DescriptionA mediator of allergic inflammation and disease
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥95%
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AssaySDS-PAGE
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Purity≥95%
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Biological activityThe ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml.
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Results2-6 ng/ml
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Molecular Weight12.7 kDa
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Storage Temp-20°C
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ShippingBlue ice
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionSterile filtered and lyophilized with no additives
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers
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Background InformationIL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolIL13, PIRC58, SNORD114-13, SNORD115-13, IGLV3-13, IGHV3OR16-13, ERVK-13, SNORD116-13, IL36G, IL25
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Short nameIL-13, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostRat
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SpeciesRat, Rats
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Alternative nameInterleukin-13, rat Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 13
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-04-07
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Entrez gene record
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 58
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-13
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-13
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 3-13 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable 3-13
- immunoglobulin lambda variable 3-13 pseudogene
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3/OR16-13 (non-functional)
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Synonyms gene name
- immunoglobulin heavy variable 3/OR16-13
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameendogenous retrovirus group K member 13
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Synonyms gene name
- endogenous retrovirus group K, member 13
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Synonyms
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GenBank acession
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Locus
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Discovery year2011-05-05
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-13
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 25
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Synonyms gene
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Synonyms gene name
- interleukin 17E
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-26
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Pubmed identfication
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Classification
- Interleukins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
