EZCellTM Cell Invasion Assay Kit (Collagen I), 12-well, 8 µm

  • Catalog number
    K917-12
  • Price
    Please ask
  • Size
    12 assays
  • Description
    Highly Sensitive and Quantitative (Fluorometric), HTP adaptable Assay to measure Cell Invasion using a Boyden Chamber
  • Summary
    • Detection method - Fluorescence (Ex/Em = 485/530 nm) • Applications: Measure cell invasion in response to stimuli. - Screen, study, or characterize compounds that influence cell invasion. - HTP adaptable
  • Detection Method
    Detection method - Fluorescence (Ex/Em = 485/530 nm)
  • Species Reactivity
    Mammalian cells
  • Applications
    • Measure cell invasion in response to stimuli • Screen and characterize compounds that influence cell invasion
  • Sample Type
    • Invasive cell lines • Invasion inhibitor or stimuli
  • Features Benefits
    • Highly sensitive fluorometric method to measure cell invasion in response to a variety of biochemical stimuli • Simple & High throughput-adaptable • Reproducible, Quantitative tool for screening, studying, and characterizing compounds that affect cell invasion
  • Storage Conditions
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf life
    12 months
  • Background
    Cell invasion is the ability of cells to migrate from one area to another through an extracellular matrix. Cell invasion is exhibited by both normal cells as well as cancerous cells in response to specific external signals, including chemical & mechanical stimuli. During invasion, extracellular matrix is enzymatically degraded by cellular proteases before cells migrate to the new location. Cell invasion is required for normal processes such as wound repair, vasculature formation and the inflammatory response as well as the abnormal invasion of tissues by tumor cells during metastasis. BioVision’s Cell Invasion Assay Kit utilizes a Boyden chamber coated with Collagen I, where the cells invade the matrix and then migrate through a semipermeable membrane in the Boyden chamber in response to stimulants or inhibitory compounds. The percent cell invasion can be analyzed directly in a plate reader. Our assay is easy to use, sensitive and adaptable to high-throughput systems.
  • Test
    Biovision supplies other types of Assays as 1.
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene
    Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
  • Gene target
  • Short name
    EZCellTM Invasion Assay Kit (Collagen I), 12- , 8 µm
  • Technique
    Assay, assays
  • Host
    Assay
  • Alternative name
    EZCellTM cellular Invasion test reagent (Collagen I), 12-well, 8 µm
  • Alternative technique
    arrays, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
  • Tissue
    cell
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