Eukaryotic Interleukin 10 IL10

Eukaryotic Interleukin 10 IL10 is available 20 times from Bioma labs

RPU54720 | Eukaryotic Interleukin 10 (IL10)size: 200 μg | 1219.52 USD

RPU54814 | Eukaryotic Interleukin 10 (IL10)size: 100 μg | 1284.87 USD

RPU54809 | Eukaryotic Interleukin 10 (IL10)size: 10 μg | 423.62 USD

RPU54720 | Eukaryotic Interleukin 10 (IL10)size: 100 μg | 987.28 USD

RPU54791 | Eukaryotic Interleukin 10 (IL10)size: 200 μg | 1494.93 USD

RPU54809 | Eukaryotic Interleukin 10 (IL10)size: 50 μg | 843.74 USD

RPU54791 | Eukaryotic Interleukin 10 (IL10)size: 100 μg | 1206.68 USD

RPU54809 | Eukaryotic Interleukin 10 (IL10)size: 100 μg | 1258.03 USD

RPU53733 | Eukaryotic Interleukin 10 (IL10)size: 100 μg | 843.74 USD

RPU53733 | Eukaryotic Interleukin 10 (IL10)size: 50 μg | 549.66 USD

RPU53733 | Eukaryotic Interleukin 10 (IL10)size: 200 μg | 995.45 USD

RPU54814 | Eukaryotic Interleukin 10 (IL10)size: 10 μg | 431.79 USD

RPU54720 | Eukaryotic Interleukin 10 (IL10)size: 10 μg | 341.93 USD

RPU54720 | Eukaryotic Interleukin 10 (IL10)size: 50 μg | 667.52 USD

RPU53733 | Eukaryotic Interleukin 10 (IL10)size: 10 μg | 309.26 USD

RPU54814 | Eukaryotic Interleukin 10 (IL10)size: 200 μg | 1590.62 USD

RPU54791 | Eukaryotic Interleukin 10 (IL10)size: 50 μg | 811.07 USD

RPU54791 | Eukaryotic Interleukin 10 (IL10)size: 10 μg | 408.45 USD

RPU54809 | Eukaryotic Interleukin 10 (IL10)size: 200 μg | 1556.78 USD

RPU54814 | Eukaryotic Interleukin 10 (IL10)size: 50 μg | 861.25 USD

• Catalog number
  RPU54814
• Supplier
  bioma
• Price
  861.25 USD
• Size
  50 μg

✓+ ()

Quantity:

• Verified reactivity
  Rattus norvegicus (Rat)
• Protein number
  P29456
• Information about sequence
  Ser19~Asn178
• Expected molecular weight
  22kDa
• Protein purity
  ≥ 90%

1. Gene info

• Identity
  5962
• Gene
  IL10
• Long gene name
  interleukin 10
• Synonyms
  • CSIF
  • TGIF
  • IL10A
  • IL-10
• Synonyms name
  • cytokine synthesis inhibitory factor
  • T-cell growth inhibitory factor
• GenBank acession
  • M57627
• Locus
  1q32.1
• Discovery year
  1991-10-31
• Entrez gene record
  3586
• Pubmed identfication
  • 9162098
• RefSeq identity
  • NM_000572
• Classification
  • Interleukins
• Havana BLAST/BLAT
  OTTHUMG00000036386

Additional information

• PubMed
  Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.

  Observational study of gene-disease association. (HuGE Navigator)

  Observational study of gene-disease association. (HuGE Navigator)

  the frequency of the TNF-alpha genotype was similar in IBS and controls

  IL-10 expression may be regulated by miR-106a, which is in turn transcriptionally regulated by Egr1 and Sp1

  Data suggest that the interaction of single nucleotide polymorphism (SNP) of interleukin-10 (IL-10) and and dopamine beta-hydroxylase (DBH) may play a role in the general symptoms on PANSS in schizophrenic patients with Tardive dyskinesia (TD).

  Depressed subjects showed significantly lower IL-10 (p=0.03, Cohen's d=-0.96), non-significantly higher IL-6, and significantly higher IL-6/IL-10 ratios (p=0.05, Cohen's d=0.50)

  Multivariate logistic regression analysis showed that IL-10 G13 and G10 alleles are independent risk factors for venous thrombosis. Furthermore, IL-10 G10 allele is more frequent in recurrent disease.

  Observational study of gene-disease association. (HuGE Navigator)

  Platelets are not only important in the early stages of the healing process (clot formation, direct release of growth factors), but also can influence the whole process of tissue regeneration by modulating synthesis and release of VEGF, bFGF and IL-10 by mononuclear leukocytes.
• Gene ontology - Biological process
  positive regulation of sequence-specific DNA binding transcription factor activity

  defense response to bacterium

  negative regulation of interleukin-6 production

  negative regulation of tumor necrosis factor production

  negative regulation of tumor necrosis factor biosynthetic process

  cytoplasmic sequestering of NF-kappaB

  cellular response to estradiol stimulus

  negative regulation of cytokine activity

  negative regulation of interleukin-8 production

  negative regulation of MHC class II biosynthetic process
• Gene ontology - Cellular component
  extracellular space

  extracellular region
• Gene ontology - Molecular function
  protein binding

  growth factor activity

  cytokine activity

  interleukin-10 receptor binding
• InterPro
  Four-helical cytokine-like, core

  Four-helical cytokine, core

  Interleukin-10, conserved site

  Interleukin-10/19/20/22/24/26 family

  Interleukin-10
• Kegg
  Cytokine-cytokine receptor interaction - Homo sapiens (human)

  Chagas disease (American trypanosomiasis) - Homo sapiens (human)

  Inflammatory bowel disease (IBD) - Homo sapiens (human)

  Pertussis - Homo sapiens (human)

  Amoebiasis - Homo sapiens (human)

  T cell receptor signaling pathway - Homo sapiens (human)

  FoxO signaling pathway - Homo sapiens (human)

  Epstein-Barr virus infection - Homo sapiens (human)

  African trypanosomiasis - Homo sapiens (human)

  Systemic lupus erythematosus - Homo sapiens (human)
• WikiPathWays
  Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways

  Allograft Rejection

  T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection

  Cytokines and Inflammatory Response
• Entrez Gene
  interleukin 10

Product images

• Gene number
  Please refer to GenBank
• Other name
  CSIF; IL10A; TGIF; Cytokine Synthesis Inhibitory Factor
• Protein origin
  293F cell
• Protein region
  Please contact us.
• Protein sequence
  Please contact us.
• Verified applications
  SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling.
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  7-11 business days
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Gene name
  Please refer to GenBank
• Gene
  Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene. Recombinant. coli interleukin-1o for cell culture or antibody production.

• Gene target
  Eukaryotic Interleukin IL10 
• Short name
  Eukaryotic Interleukin 10 (IL10)
• Alternative name
  Eukaryotic Interleukin 10 (interleukin 10)
• Alternative to gene target
  interleukin 10, CSIF and GVHDS and IL-10 and IL10A and TGIF, IL10 and IDBG-106270 and ENSG00000136634 and 3586, growth factor activity, Extracellular, Il10 and IDBG-190697 and ENSMUSG00000016529 and 16153, IL10 and IDBG-629159 and ENSBTAG00000006685 and 281246

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