EPZ004777 for cell activation

EPZ004777 for cell activation is available 2 times from Biovision labs

2381-5 | EPZ004777 for cell activationsize: 5 mg | 547.32 USD

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2381-1 | EPZ004777 for cell activationsize: 1 mg | 191.39 USD

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  • Description
    A potent and selective DOT1L inhibitor. Treatment of leukemic cells with EPZ004777 results in selective killing of those cells bearing the MLL (mixed lineage leukemia) gene translocation, with little effect on non-MLL-translocated cells.
  • Peptide sequence
    N/A
  • CAS number
    1338466-77-5
  • Molecular weight
    539.67
  • Category
    Biochemicals
  • Other name
    1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea
  • Molecular formula
    C₂₈H₄₁N₇O₄
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO
  • Storage condition
    -20 ̊C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from light and air
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    EPZ004777 for activation
  • Technique
    activation
  • Alternative name
    EPZ004777 to measure cellular activation
  • Tissue
    cell
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