Episialin, EMA Antibody ( GP1.4)

1x Episialin, EMA Antibody ( GP1.4) found in boster

  • Target antigen
    Episialin, EMA
  • Clonality
    Monoclonal antibody
  • Clone
    GP1.4
  • Raised in
    mice
  • Type of the antibody
    IgG1 monoclonal antibody
  • Product form
    freeze-dried
  • Reacts with species:
    Human
  • Analyses
    IHC-P,IHC-F
  • Immunogen
    Human milk fat globule membranes.
  • Product configuration
    Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
  • Purification
    Ascites
  • Solubilization
    The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
  • Storage condtions
    Keep the Episialin, EMA Antibody ( GP1.4)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The Episialin, EMA Antibody ( GP1.4) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1(EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type I transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
  • Related articles
    1. Lu, W.; Hisatsune, A.; Koga, T.; Kato, K.; Kuwahara, I.; Lillehoj, E. P.; Chen, W.; Cross, A. S.; Gendler, S. J.; Gewirtz, A. T.; Kim, K. C. : Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice. J. Immun. 176: 3890-3894, 2006. 2. Sood, R.; Zehnder, J. L.; Druzin, M. L.; Brown, P. O. : Gene expression patterns in human placenta. Proc. Nat. Acad. Sci. 103: 5478-5483, 2006. 3. Wei, X.; Xu, H.; Kufe, D. : MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. Molec. Cell 21: 295-305, 2006.
  • Gene Name
    MUC1
  • Protein Name
    Mucin-1
  • Gene Full Name
    mucin 1, cell surface associated
  • Synonyms
    CD227|EMA|PEM|PEMT|KL-6|PUM|MUCIN 1, URINARY|Episialin|H23AG|PEANUT-REACTIVE URINARY MUCIN|MUCIN, TUMOR-ASSOCIATED EPITHELIAL|POLYMORPHIC EPITHELIAL MUCIN|EPITHELIAL MEMBRANE ANTIGEN|mucin 1, transmembrane|Breast carcinoma-associated antigen DF3|Carcinoma-associated mucin|Krebs von den Lungen-6|Peanut-reactive urinary mucin|Polymorphic epithelial mucin|Tumor-associated epithelial membrane antigen|Tumor-associated mucin
  • Uniprot ID
    Human(15941), Mouse(02496), Rat(B2GV31)
  • Entrez GeneID
    Human(4582), Mouse(17829), Rat(24571)
  • Gene target
  • Short name
    Episialin, EMA Antibody ( GP1.4)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Episialin, EMA (Antibody to) ( GP1.4)
  • Alternative technique
    antibodies

MA1039 | Episialin, EMA Antibody ( GP1.4)0,1 mg 390.5 USD

  • Catalog number
    MA1039
  • Supplier
  • Price
    390.5 USD
  • Size
    0,1 mg
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
1. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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