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Chemical available in other sizes
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Stock availability
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Cas number
136470-79-6
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Chemical s molecular weight
286.33
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Chemical s main applications
ent-Abacavir is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
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Chemical s category
Anti-virals, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir;
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Chemical s formula
C14H18N6O
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Physical properties
No Data Available
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
No Data Available
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Stability conditions
No Data Available
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Storage
No Data Available
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