Emerin Antibody, ALEXA FLUOR 555

• Catalog number
  bs-6660R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  Emerin Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-Emerin PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Emerin
• Specificity
  This is a highly specific antibody against Emerin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Emerin
• Gene ID Number
  2010
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity; Skeletal muscle, heart, colon, testis, ovary and pancreas.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  EDMD; EMD; EMD_HUMAN; Emerin; Emery Dreuss muscular dystrophy; STA.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  Emerin  
• Gene symbol
  EMD, LEMD2
• Short name
  Anti-Emerin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  Emerin Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3331
• Gene
  EMD
• Long gene name
  emerin
• Synonyms gene name
  • Emery-Dreifuss muscular dystrophy
• Synonyms
  • STA
  • LEMD5
• Synonyms name
  • LEM domain containing 5
• GenBank acession
  • X82434
• Locus
  Xq28
• Discovery year
  2001-06-22
• Entrez gene record
  2010
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000033186
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • UMD Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • Global Variome shared LOVD
  • LRG_745

Gene info

• Identity
  HGNC:21244
• Gene
  LEMD2
• Long gene name
  LEM domain nuclear envelope protein 2
• Synonyms gene name
  • LEM domain containing 2
• Synonyms
  • dJ482C21.1
  • NET25
  • LEM2
• Synonyms name
  • lamina-associated polypeptide-emerin-MAN1 domain containing 2
• Locus
  6p21.31
• Discovery year
  2003-05-29
• Entrez gene record
  221496
• Pubmed identfication
  • 16339967
  • 28056360
  • 28242692
  • 31147383
• RefSeq identity
  • NM_181336
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000014535

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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