eIF3F Antibody ALEXA FLUOR

eIF3F Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-3841R-A350 | eIF3F Antibody, ALEXA FLUOR 350size: 100ul | 379.53 USD

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bs-3841R-A488 | eIF3F Antibody, ALEXA FLUOR 488size: 100ul | 379.53 USD

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bs-3841R-A555 | eIF3F Antibody, ALEXA FLUOR 555size: 100ul | 379.53 USD

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bs-3841R-A594 | eIF3F Antibody, ALEXA FLUOR 594size: 100ul | 379.53 USD

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bs-3841R-A647 | eIF3F Antibody, ALEXA FLUOR 647size: 100ul | 379.53 USD

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  • Category
    Conjugated Primary Antibodies
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    e3F
  • Specificity
    This is a highly specific antibody against e3F.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    135-185/357
  • Subcellular location
    Cytoplasm
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human eIF3F
  • Gene ID Number
    8665
  • Swiss Prot
    O00303
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross-reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Synonyms
    EIF3S5; eIF3-p47; Eukaryotic translation initiation factor 3 subunit F; eIF3f; Deubiquitinating enzyme eIF3f; Eukaryotic translation initiation factor 3 subunit 5; eIF-3-epsilon; eIF3 p47
  • Gene target
  • Short name
    eIF3F Antibody,
  • Technique
    Antibody
  • Alternative technique
    antibodies
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