DTX3L Antibody

• Catalog number
  bs-14438R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DTX3L Primary Polyclonal Antibody
• Also known as
  DTX3L PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DTX3L
• Specificity
  This is a highly specific antibody against DTX3L.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  720-738/740
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTX3L
• Gene ID number
  151636
• Swiss Prot
  Q8TDB6
• Tested Applications
  WB
• Recommended dilutions
  WB(1:100-1000)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BBAP; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BAL-associated protein; Protein deltex-3-like; Rhysin-2; Rhysin2; DTX3L
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DTX3L  
• Gene symbol
  DTX3L
• Short name
  Anti-DTX3L
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DTX3L Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30323
• Gene
  DTX3L
• Long gene name
  deltex E3 ubiquitin ligase 3L
• Synonyms gene name
  • deltex 3-like (Drosophila)
• Synonyms
  • BBAP
  • RNF143
• Synonyms name
  • rhysin 2
• Locus
  3q21.1
• Discovery year
  2004-12-03
• Entrez gene record
  151636
• Pubmed identfication
  • 12670957
  • 22411408
• RefSeq identity
  • NM_138287
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000159524

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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