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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
285983-48-4
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Chemical s molecular weight
527.66
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Chemical s main applications
Doramapimod is a highly potent inhibitor of p38 mitogen-activated protein kinase (MAPK). Doramapimod is a potential agent for the treatment of inflammatory diseases. Doramapimod blocks baseline and bortezomib-triggered upregulation of p38 MAPK and Hsp27 phosphorylation leading to enhanced cytotoxicity and caspase activation.
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Chemical s category
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
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Other name
N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea; BIRB 796BS; Birb 796;
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Chemical s formula
C31H37N5O3
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Physical properties
Pale Beige Solid
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Melting temperature
>136°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO, Methanol
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Stability conditions
No Data Available
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Storage
Refrigerator
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