Dofetilide for cell activation

Dofetilide for cell activation is available 2 times from Biovision labs

B1189-5 | Dofetilide for cell activationsize: 5 mg | 167.18 USD

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B1189-25 | Dofetilide for cell activationsize: 25 mg | 487.4 USD

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  • Description
    Dofetilide is a class III antiarrhythmic agent and inhibits the rapid delayed rectifier K⁺current (IKr) with IC₅₀values of 31.5 nM in guinea pig cardiomyocytes. At higher doses it demonstrates pro-arrhythmic activity in cell models. Therefore, dofetilide has been cautiously used in the treatment of atrial fibrillation, the conversion of flutter to sinus rhythm and in the maintenance of sinus rhythm after conversion.
  • Peptide sequence
    N/A
  • CAS number
    115256-11-6
  • Molecular weight
    441.56
  • Category
    Biochemicals
  • Other name
     1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
  • Molecular formula
    C₁₉H₂₇N₃O₅S₂
  • Physical appearance
    White Solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (25 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Dofetilide for activation
  • Technique
    activation
  • Alternative name
    Dofetilide to measure cellular activation
  • Tissue
    cell
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