DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)

• Catalog number
  GEN603492
• Price
  Please ask
• Size
  500ul

• Also known as
  DNA PK, Catalytic Subunit
• Other names
  DNA-dependent protein kinase catalytic subunit isoform 1; DNA-dependent protein kinase catalytic subunit; DNA-dependent protein kinase catalytic subunit; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1; protein kinase, DNA-activated, catalytic polypeptide; DNPK1; p460
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  PRKDC; PRKDC; HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; HYRC; HYRC1; DNA-PK catalytic subunit; DNA-PKcs
• Gene name synonims
  PRKDC; PRKDC; HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; HYRC; HYRC1; DNA-PK catalytic subunit; DNA-PKcs
• Other gene names
  PRKDC; PRKDC; HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; HYRC; HYRC1; DNA-PK catalytic subunit; DNA-PKcs
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  3F148
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Inhibits ~50% of the kinase activity of DNAPKcs. Preincubation of enzyme with DNA protects DNA-PKcs against inactivation. Species Crossreactivity: human and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See D3949-11X
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze atStore the antibody at -20 degrees Celsius. or colder. Aliquots are stable for at least 12 months atStore the antibody at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)

• Gene target
  DNA   Catalytic   Subunit   DNA-dependent   Protein   Kinase  
• Gene symbol
  PRKDC, HLA-DOA
• Short name
  DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)
• Technique
  dna
• Alternative name
  Anti-DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

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