DKK3 Antibody, Cy3 Conjugated
DKK3 Antibody, Cy3 Conjugated is available 1 time from Bioss primary conjugated antibodies labs
- Long nameDKK3 Polyclonal Antibody, Cy3 Conjugated
- CategoryConjugated Primary Antibodies
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenDKK3
- SpecificityThis is a highly specific antibody against DKK3.
- Modification siteNone
- ClonePolyclonal antibody
- Concentration1ug per 1ul
- Subcellular locationSecreted
- SourceKLH conjugated synthetic peptide derived from human DKK3
- Gene ID number27122
- Swiss ProtQ9UBP4
- Tested applicationsFCM, IF(IHC-P)
- Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundAntagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission512,550nm/570,615nm
- SynonymsRIG; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3; DKK3; UNQ258/PRO295
- Gene target
- Short nameDKK3 Antibody, Conjugated
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative nameDKK3 (Antibody to), cyanine 3 coupled
- Alternative techniqueantibodies
bs-2686R-Cy3 | DKK3 Antibody, Cy3 Conjugatedsize: 0.1ml | 430.54 USD
- Catalog numberbs-2686R-Cy3
- Price430.54 USD
- PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the DKK3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
- Additional conjugationcy3 conjugation kit
- French translationanticorps
1. Gene info
- Long gene namedickkopf WNT signaling pathway inhibitor 3
- Synonyms gene name
- dickkopf (Xenopus laevis) homolog 3
- dickkopf 3 homolog (Xenopus laevis)
- Synonyms name
- GenBank acession
- Discovery year2000-09-01
- Entrez gene record
- Pubmed identfication
- RefSeq identity
- Havana BLAST/BLAT
- ConceptScope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMeddata do not support that thyroxine-binding protein p29 has a functional relationship with D2, but expression of p29 in the blood-CSF barrier suggests that it might be involved in T(4) transport to and from the CSFWNT7A can specifically act via a Frizzled-5.LRP6 receptor complex in PC12 cells and that this activity can be antagonized by Dickkopf-1 and Dickkopf-3.
- Gene ontology - Biological process
- Gene ontology - Cellular component
- Entrez Gene
Supplier:Bioss Polyclonal Antibodies
Supplier:Bioss Primary Unconjugated Antibodies
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