Di-(tert-Butyl-dimethylsilyl) Curcumin

Chemical available in other sizes

Please inquire size and price
Stock availability

In Stock
Cas number

1134639-23-8
Chemical s molecular weight

596.9
Chemical s main applications

Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Chemical s category

Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Other name

(1E,4Z,6E)-1,7-Bis[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
Chemical s formula

C33H48O6Si2
Physical properties

Yellow Solid
Melting temperature

138-140ºC
Boiling temperature

No Data Available
Chemical s soluble in

Chloroform (Slightly), Methanol (Slightly)
Stability conditions

No Data Available
Storage

Refrigerator
Chemical s specifications

Gene target

tert-Butyl-dimethylsilyl Curcumin
Short name

Di-(tert-Butyl-dimethylsilyl) Curcumin
Alternative name

Di-(telomerase reverse transcriptase-Butyl-dimethylsilyl) Curcumin
Alternative to gene target

telomerase reverse transcriptase, CMM9 and DKCA2 and DKCB4 and EST2 and hEST2 and hTRT and PFBMFT1 and TCS1 and TP2 and TRT, TERT and IDBG-10998 and ENSG00000164362 and 7015, telomeric RNA binding, nuclei, Tert and IDBG-165912 and ENSMUSG00000021611 and 21752, BT.60929 and IDBG-632169 and ENSBTAG00000012567 and 518884