Di-O-cysteinyl-glycinoyl Curcumin-d6
-
Catalog numberD455602
-
PricePlease ask
-
Size0,5 mg
-
-
Chemical available in other sizesPlease inquire size and price
-
Stock availabilityPlease Inquire
-
Cas numberThis product doesn't have CAS Number
-
Chemical s molecular weight694.81
-
Chemical s main applicationsDi-O-cysteinyl-glycinoyl Curcumin-d6 is the isotope labelled analog of Di-O-cysteinyl-glycinoyl Curcumin. Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease (Chem. and Eng. News 90(31), 44 (2012)).
-
Chemical s categoryAmino Acids & Derivatives, Aromatics, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
-
Other name4-((1E,6E)-7-(4-(2-((R)-2-Amino-3-mercaptopropanamido)acetoxy)-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenyl 2-((S)-2-amino-3-mercaptopropanamido)acetate-d6; 2,2'-[[(1E,6E)-3,5-dioxo-1,6-heptadiene-1,7-diyl]bis(2-methoxy-4,1-phenylene)] Ester L-cysteinyl-glycine-d6;
-
Chemical s formulaC31H30D6N4O10S2
-
Physical propertiesNo Data Available
-
Melting temperatureNo Data Available
-
Boiling temperatureNo Data Available
-
Chemical s soluble inNo Data Available
-
Stability conditionsNo Data Available
-
StorageNo Data Available
-
Gene target
-
Gene symbolCENPO, H4C15, POFUT1, SDR9C7, GNAO1, H3C15, FABP3, H2BC19P, OGT, AOPEP
-
Short nameDi-O-cysteinyl-glycinoyl Curcumin-d6
-
Alternative nameDi-O-cysteinyl-glycinoyl Curcumin-d6
-
Gene info
-
Identity
-
Gene
-
Long gene namecentromere protein O
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2006-06-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Constitutive centromere associated network
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameH4 clustered histone 15
-
Synonyms gene
-
Synonyms gene name
- histone 2, H4b
- histone cluster 2, H4b
- histone cluster 2 H4 family member b
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2006-06-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- H4 histones
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprotein O-fucosyltransferase 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-10-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- MicroRNA protein coding host genes
- Fucosyltransferases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameshort chain dehydrogenase/reductase family 9C member 7
-
Synonyms gene name
- short chain dehydrogenase/reductase family 9C, member 7
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-12-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Short chain dehydrogenase/reductase superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameG protein subunit alpha o1
-
Synonyms gene name
- guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
-
Synonyms
-
Locus
-
Discovery year1988-04-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- G protein subunits alpha, group i
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameH3 clustered histone 15
-
Synonyms gene
-
Synonyms gene name
- histone 2, H3a
- histone cluster 2, H3a
- histone cluster 2 H3 family member a
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-02-19
-
Entrez gene record
-
Pubmed identfication
-
Classification
- H3 histones
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefatty acid binding protein 3
-
Synonyms gene
-
Synonyms gene name
- fatty acid binding protein 11
- fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
- fatty acid binding protein 3, muscle and heart
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-08-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fatty acid binding protein family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameH2B clustered histone 19, pseudogene
-
Synonyms gene
-
Synonyms gene name
- histone 2, H2bd
- H2B histone family, member O
- histone cluster 2, H2bd (pseudogene)
- histone cluster 2 H2B family member d (pseudogene)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-02-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- H2B histones
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameO-linked N-acetylglucosamine (GlcNAc) transferase
-
Synonyms gene name
- O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-12-03
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- O-linked N-acetylglucosaminyltransferases
- NSL histone acetyltransferase complex
- Tetratricopeptide repeat domain containing
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameaminopeptidase O (putative)
-
Synonyms gene
-
Synonyms gene name
- chromosome 9 open reading frame 3
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-01-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M1 metallopeptidases
- MicroRNA protein coding host genes
-
VEGA ID
