Degenerative Spermatocyte Homolog 2 - Blocking Peptide

  • Catalog number
    X2358B
  • Price
    Please ask
  • Size
    50 μg
  • Category
    Proteins & Peptides
  • Long description
    Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Belongs to the fatty acid desaturase family. DEGS subfamily. Highly expressed in skin, intestine and kidney.
  • Antibody come from
    peptide
  • Other description
    Provided as solution in phosphate buffered saline with 0.08% sodium azide.
  • Clone
    not specified
  • Antigen antibody binding interaction
    Degenerative Spermatocyte Homolog 2 - Blocking Peptide
  • Antibody is raised in
    Rabbit
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    Western blot
  • Antibody s suited for
    For use with SET polyclonal antibodies (Cat. No. X2088P & X2332P).
  • Storage
    -80ºC
  • Relevant references
    [1] von Lindern M., van Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G.;_x000B_ Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.;_x000B_Mol. Cell. Biol. 12:3346-3355(1992)._x000B_[2] von Lindern M., van Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G.;_x000B_Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.;_x000B_Mol. Cell. Biol. 12:3346-3355(1992)._x000B_[3] Vaesen M., Barnikol-Watanabe S., Goetz H., Adil Awni L., Cole T., Zimmermann B., Kratzin H.D., Hilschmann N.;_x000B_Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.;_x000B_Biol. Chem. Hoppe-Seyler 375:113-126(1994)._x000B_[4] Nagata K., Kawase H., Handa H., Yano K., Yamasaki M., Ishimi Y., Okuda A., Kikuchi A., Matsumoto K.;_x000B_Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis.;_x000B_Proc. Natl. Acad. Sci. U.S.A. 92:4279-4283(1995)._x000B_[5] Li M., Makkinje A., Damuni Z.;_x000B_The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A.;_x000B_J. Biol. Chem. 271:11059-11062(1996)._x000B_[6] Tsujio I., Zaidi T., Xu J., Kotula L., Grundke-Iqbal I., Iqbal K.;_x000B_Inhibitors of protein phosphatase-2A from human brain: structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated Tau.;_x000B_Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases._x000B_[7] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).;_x000B_Genome Res. 14:2121-2127(2004)._x000B_[8] Adachi Y., Pavlaki G.N., Copeland T.D.;_x000B_Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia.;_x000B_J. Biol. Chem. 269:2258-2262(1994)._x000B_[9] Wang L.C., Chen Y.;_x000B_A relative factor in human rectum carcinoma.;_x000B_Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases._x000B_[10] Carlson S.G., Eng E., Kim E.-G., Perlman E.J., Copeland T.D., Ballermann B.J.;_x000B_Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor.;_x000B_J. Am. Soc. Nephrol. 9:1873-1880(1998)._x000B_[11] Seo S.-B., McNamara P., Heo S., Turner A., Lane W.S., Chakravarti D.;_x000B_Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the Set oncoprotein.;_x000B_Cell 104:119-130(2001)._x000B_[12] Minakuchi M., Kakazu N., Gorrin-Rivas M.J., Abe T., Copeland T.D., Ueda K., Adachi Y.; Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.;_x000B_Eur. J. Biochem. 268:1340-1351(2001)._x000B_[13] Fan Z., Beresford P.J., Zhang D., Lieberman J.;_x000B_HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.;_x000B_Mol. Cell. Biol. 22:2810-2820(2002)._x000B_[14] Fan Z., Beresford P.J., Oh D.Y., Zhang D., Lieberman J.;_x000B_Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.;_x000B_Cell 112:659-672(2003)._x000B_[15] Fan Z., Beresford P.J., Oh D.Y., Zhang D., Lieberman J.;_x000B_Cell 115:241-241(2003)._x000B_[16] Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.;_x000B_Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.;_x000B_Cell 127:635-648(2006)._x000B_[17] Sprung R., Chen Y., Xu Y., Ball H., Pei J., Cheng T., Kho Y., Xiao H., Xiao L., Grishin N.V., White M., Yang X.-J., Zhao Y.;_x000B_Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.;_x000B_Mol. Cell 23:607-618(2006)._x000B_[18] Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;_x000B_Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.;_x000B_Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Test
    You can block the antibody by the specific target amino acid sequence of peptide.
  • Properties
    blocking peptide
  • Description
    Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
  • Gene target
  • Gene symbol
    DEGS2
  • Short name
    Degenerative Spermatocyte Homolog 2 - Blocking Peptide
  • Technique
    blocking peptide, Blocking, peptide, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
  • Isotype
    not specified
  • Label
    unlabeled
  • Alternative name
    Degenerative Spermatocyte Homolog 2 - inhibiting short protein sequence
  • Alternative technique
    control, peptides
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: A count of SPERM in the ejaculum, expressed as number per milliliter.
  • Tree numbers
    • E01.370.225.500.195.870
    • E01.370.225.992.624
    • E05.200.500.195.870
    • E05.200.992.624
    • E05.242.195.870
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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