DAG1 (Tyr892) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-4075R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  DAG1 (Tyr892) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-DAG1 Tyr892 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DAG1 Tyr892
• Specificity
  This is a highly specific antibody against DAG1 Tyr892.
• Modification
  Phosphorylation
• Modification Site
  Tyr892
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human DAG1 around the phosphorylation site of Tyr892
• Gene ID Number
  1605
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  DAG1 Tyr892; DAG1 Y892; p-DAG1Tyr892; Alpha Dystroglycan phospho Y892; AGRNR; Alpha-DG; Beta-DG; Beta-dystroglycan; beta Dystroglycan; DAG; Dag1; DAG1_HUMAN; Dystroglycan 1 dystrophin-associated glycoprotein 1; Dystroglycan; Dystrophin-associated glycoprotein 1; 156DAG; A3a; Dystrophin-associated glycoprotein 1.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DAG1 Tyr892 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  DAG1   Tyr892  
• Gene symbol
  DAG1
• Short name
  Anti-DAG1 Tyr892
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  DAG1 (Tyr892) Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  dystroglycan 1 (dystrophin-associated glycoprotein 1), 156DAG and A3a and AGRNR and DAG and MDDGC7 and MDDGC9, DAG1 and IDBG-34876 and ENSG00000173402 and 1605, alpha-actinin binding, nuclei, Dag1 and IDBG-199494 and ENSMUSG00000039952 and 13138, BT.88492 and IDBG-645991 and ENSBTAG00000011580 and 281439

Gene info

• Identity
  HGNC:2666
• Gene
  DAG1
• Long gene name
  dystroglycan 1
• Synonyms gene name
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
• Synonyms
  • A3a
  • 156DAG
  • AGRNR
  • DAG
• Synonyms name
  • alpha-dystroglycan
  • dystrophin-associated glycoprotein-1
  • beta-dystroglycan
• GenBank acession
  • L19711
• Locus
  3p21.31
• Discovery year
  1997-07-22
• Entrez gene record
  1605
• Pubmed identfication
  • 7774920
  • 1741056
• VEGA ID
  OTTHUMG00000156869
• Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • LRG_854

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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