CXCR5 Antibody

• Catalog number
  R31129
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CXCR5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the CXCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CXCR5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P32302
• Purity
  Antigen affinity
• Description
  Chemokine CXC Motif Receptor 5, also known as BLR1, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).
• Immunogen
  An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 5 (SSLSESENATSLTTF) was used as the immunogen for this CXCR5 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the CXCR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CXCR5  
• Gene symbol
  CXCR5
• Short name
  Anti-CXCR5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CXCR5
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-X-C motif) receptor 5, BLR1 and CD185 and MDR15, CXCR5 and IDBG-74047 and ENSG00000160683 and 643, C-X-C chemokine receptor activity, Cell surfaces, Cxcr5 and IDBG-157659 and ENSMUSG00000047880 and 12145, BLR1 and IDBG-631448 and ENSBTAG00000046320 and 497021

Gene info

• Identity
  HGNC:1060
• Gene
  CXCR5
• Long gene name
  C-X-C motif chemokine receptor 5
• Synonyms gene
  • BLR1
• Synonyms gene name
  • Burkitt lymphoma receptor 1, GTP-binding protein
  • Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
  • chemokine (C-X-C motif) receptor 5
• Synonyms
  • MDR15
  • CD185
• GenBank acession
  • X68829
• Locus
  11q23.3
• Discovery year
  1993-06-29
• Entrez gene record
  643
• Pubmed identfication
  • 1425907
• RefSeq identity
  • NM_001716
• Classification
  • C-X-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000166345

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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