CXCR4 Antibody

CXCR4 Antibody is available 3 times from Boster labs

  • Target antigen
    CXCR4
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the CXCR4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The CXCR4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    CXCR4 (Chemokine,CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.
  • Related articles
    1. Caruz, A.; Samsom, M.; Alonso, J. M.; Alcami, J.; Baleux, F.; Virelizier, J. L.; Parmentier, M.; Arenzana-Seisdedos, F. : Genomic organization and promoter characterization of human CXCR4 gene. FEBS Lett. 426: 271-278, 1998. 2. Tachibana, K.; Hirota, S.; Iizasa, H.; Yoshida, H.; Kawabata, K.; Kataoka, Y.; Kitamura, Y.; Matsushima, K.; Yoshida, N.; Nishikawa, S.; Kishimoto, T.; Nagasawa, T. : The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393: 591-594, 1998.
  • Gene Name
    CXCR4
  • Uniprot ID
    P61073
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    CXCR4 Antibody
  • Technique
    Antibody
  • Alternative name
    chemokine (C-X-C motif) receptor 4 (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    chemokine (C-X-C motif) receptor 4, CD184 and D2S201E and FB22 and HM89 and HSY3RR and LAP-3 and LAP3 and LCR1 and LESTR and NPY3R and NPYR and NPYRL and NPYY3R and WHIM, CXCR4 and IDBG-71032 and ENSG00000121966 and 7852, this GO :0000187 and activation of MAPK activity and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0001667 and ameboidal cell migration and biological process this GO :0001764 and neuron migration and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007281 and germ cell development and biological process this GO :0007420 and brain development and biological process this GO :0008045 and motor neuron axon guidance and biological process this GO :0008354 and germ cell migration and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019955 and cytokine binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030260 and entry into host cell and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030426 and growth cone and cellular component this GO :0031252 and cell leading edge and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032027 and myosin light chain binding and molecular function this GO :0042098 and T cell proliferation and biological process this GO :0042119 and neutrophil activation and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043217 and myelin maintenance and biological process this GO :0045087 and innate immune response and biological process this GO :0048699 and generation of neurons and biological process this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0050920 and regulation of chemotaxis and biological process this GO :0061351 and neural precursor cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process, ubiquitin binding, this GO :0001618: virus receptor activity and also this GO :0003779: actin binding and also this GO :0004930: G-protein coupled receptor activity and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0016494: C-X-C chemokine receptor activity and also this GO :0019955: cytokine binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0032027: myosin light chain binding and also this GO :0043130: ubiquitin binding, this GO :0001618: virus receptor activity, this GO :0003779: actin binding, this GO :0004930: G-protein coupled receptor activity, this GO :0005515: protein binding, this GO :0015026: coreceptor activity, this GO :0016494: C-X-C chemokine receptor activity, this GO :0019955: cytokine binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0032027: myosin light chain binding, this GO :0043130: ubiquitin binding, Cell surfaces, Cxcr4 and IDBG-189999 and ENSMUSG00000045382 and 12767, CXCR4 and IDBG-642187 and ENSBTAG00000001060 and 281736

PA1237 | CXCR4 Antibodysize: 0,1 mg | 393.89 USD

Ajax processing

PA2081 | CXCR4 Antibodysize: 0,1 mg | 393.89 USD

Ajax processing

A00031 | CXCR4 Antibodysize: 0,1 mg | 460.36 USD

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