CXCR3 Antibody
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Catalog numberR31506
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenCXCR3
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P
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Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the CXCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis CXCR3 antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID2833
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PurityAntigen affinity
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DescriptionCXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. Signaling is associated with MG pathogenesis and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.
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ImmunogenHuman partial recombinant protein (AA 1-368) was used as the immunogen for this CXCR3 antibody.
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StorageAfter reconstitution, the CXCR3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCXCR3
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Short nameAnti-CXCR3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to CXCR3
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-X-C motif) receptor 3, CD182 and CD183 and CKR-L2 and CMKAR3 and GPR9 and IP10-R and Mig-R and MigR, CXCR3 and IDBG-76333 and ENSG00000186810 and 2833, C-X-C chemokine binding, Cell surfaces, Cxcr3 and IDBG-164788 and ENSMUSG00000050232 and 12766, CXCR3 and IDBG-635748 and ENSBTAG00000014798 and 497018
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Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine receptor 3
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 9
- chemokine (C-X-C motif) receptor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-01
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Entrez gene record
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Pubmed identfication
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Classification
- C-X-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data