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Target antigen
CXCL2
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
mouse, rat
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Analyses
WB,ELISA
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Immunogen
E. coli-derived rat CXCL2 recombinant protein (Position: S32-N100). Rat CXCL2 shares 62.3% and 88.4% amino acid (aa) sequence identity with huamn and mouse CXCL2, respectively.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the CXCL2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The CXCL2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2(Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
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Related articles
1. Iida N., Grotendorst G.R. Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue. Mol. Cell. Biol. 10:5596-5599, 1990. 2. Pelus LM, Fukuda S. Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp Hematol. 2006 Aug;34(8):1010-20. 3. Wolpe, S. D., Sherry, B., Juers, D., Davatelis, G., Yurt, R. W., Cerami, A. Identification and characterization of macrophage inflammatory protein 2. Proc. Nat. Acad. Sci. 86: 612-616, 1989.
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Gene Name
CXCL2
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Protein Name
C-X-C motif chemokine 2
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Gene Full Name
chemokine (C-X-C motif) ligand 2
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Synonyms
C-X-C motif chemokine 2 antibody|Chemokine (C X C motif) ligand 2 antibody|Chemokine, CXC motif, ligand 2 antibody|CINC 2a antibody| CINC2a antibody|CINC3 antibody|CXC chemokine antibody|CXCL 2 antibody|Cxcl2 antibody|CXCL2_HUMAN antibody|Cytokine-induced neutrophil chemoattractant 3 antibody|GRO 2 antibody|GRO b antibody|GRO protein, beta antibody|Gro-beta antibody|GRO-beta(5-73) antibody|GRO-beta-T antibody|GRO2 antibody|GRO2 oncogene antibody|GROb antibody|GRObeta antibody|Growth regulated protein beta antibody|Growth-regulated protein beta antibody|GROX antibody|Hematopoietic synergistic factor antibody|HSF antibody|Macrophage inflammatory protein 2 alpha antibody|Macrophage inflammatory protein 2 antibody|Macrophage inflammatory protein 2-alpha antibody|Melanoma growth stimulatory activity beta antibody|MGSA b antibody|MGSA beta antibody|MIP 2 antibody|MIP 2a antibody|MIP2 alpha antibody|MIP2 antibody|MIP2-alpha antibody|MIP2A antibody|MIP2alpha antibody|SB-251353 antibody|SCYB 2 antibody|Scyb antibody|SCYB2 antibody|Small inducible cytokine subfamily B, member 2 antibody
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Uniprot ID
P30348
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Entrez GeneID
114105
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
