CPA3/MC-CPA Antibody

• Catalog number
  bs-12338R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CPA3/MC-CPA Primary Polyclonal Antibody
• Also known as
  CPA3/MC-CPA PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CPA3/MC-CPA
• Specificity
  This is a highly specific antibody against CPA3/MC-CPA.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
• Gene ID number
  1359
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  carboxypeptidase A; Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; Mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CPA3/MC-CPA  
• Gene symbol
  CPA3, CPA1, CPA4
• Short name
  Anti-CPA3/MC-CPA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CPA3/MC-CPA Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  carboxypeptidase A3 (mast cell), MC-CPA, CPA3 and IDBG-60396 and ENSG00000163751 and 1359, zinc ion binding, Extracellular, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454

Gene info

• Identity
  HGNC:2298
• Gene
  CPA3
• Long gene name
  carboxypeptidase A3
• Synonyms gene name
  • carboxypeptidase A3 (mast cell)
• Synonyms name
  • mast cell carboxypeptidase A
  • tissue carboxypeptidase A
• Locus
  3q24
• Discovery year
  1990-06-13
• Entrez gene record
  1359
• RefSeq identity
  • NM_001870
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000159526

Gene info

• Identity
  HGNC:2296
• Gene
  CPA1
• Long gene name
  carboxypeptidase A1
• Synonyms gene
  • CPA
• Synonyms gene name
  • carboxypeptidase A1 (pancreatic)
• Synonyms name
  • pancreatic carboxypeptidase A
• Locus
  7q32.2
• Discovery year
  1986-01-01
• Entrez gene record
  1357
• RefSeq identity
  • NM_001868
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000157826

Gene info

• Identity
  HGNC:15740
• Gene
  CPA4
• Long gene name
  carboxypeptidase A4
• Synonyms
  • CPA3
• Synonyms name
  • carboxypeptidase A3
• GenBank acession
  • AF095719
• Locus
  7q32.2
• Discovery year
  2001-05-24
• Entrez gene record
  51200
• Pubmed identfication
  • 10383164
  • 10860668
• RefSeq identity
  • NM_016352
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000157825
• Locus Specific Databases
  • LRG_1038

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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