CPA3/MC-CPA Antibody, Cy3 Conjugated

• Catalog number
  bs-12338R-Cy3
• Price
  Please ask
• Size
  0.1ml

• Long name
  CPA3/MC-CPA Polyclonal Antibody, Cy3 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy3
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CPA3/MC-CPA
• Specificity
  This is a highly specific antibody against CPA3/MC-CPA.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
• Gene ID number
  1359
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  512,550nm/570,615nm
• Synonyms
  carboxypeptidase A; Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; Mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-CPA3/MC-CPA can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
• Additional conjugation
  cy3 conjugation kit
• French translation
  anticorps

• Gene target
  CPA3/MC-CPA   Conjugated  
• Gene symbol
  CPA3, CPA1, CPA4
• Short name
  Anti-CPA3/MC-CPA
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy3
• Alternative name
  Anti-CPA3/MC-CPA PAb Cy3
• Alternative technique
  antibodies
• Alternative to gene target
  carboxypeptidase A3 (mast cell), MC-CPA, CPA3 and IDBG-60396 and ENSG00000163751 and 1359, zinc ion binding, Extracellular, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454

Gene info

• Identity
  HGNC:2298
• Gene
  CPA3
• Long gene name
  carboxypeptidase A3
• Synonyms gene name
  • carboxypeptidase A3 (mast cell)
• Synonyms name
  • mast cell carboxypeptidase A
  • tissue carboxypeptidase A
• Locus
  3q24
• Discovery year
  1990-06-13
• Entrez gene record
  1359
• RefSeq identity
  • NM_001870
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000159526

Gene info

• Identity
  HGNC:2296
• Gene
  CPA1
• Long gene name
  carboxypeptidase A1
• Synonyms gene
  • CPA
• Synonyms gene name
  • carboxypeptidase A1 (pancreatic)
• Synonyms name
  • pancreatic carboxypeptidase A
• Locus
  7q32.2
• Discovery year
  1986-01-01
• Entrez gene record
  1357
• RefSeq identity
  • NM_001868
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000157826

Gene info

• Identity
  HGNC:15740
• Gene
  CPA4
• Long gene name
  carboxypeptidase A4
• Synonyms
  • CPA3
• Synonyms name
  • carboxypeptidase A3
• GenBank acession
  • AF095719
• Locus
  7q32.2
• Discovery year
  2001-05-24
• Entrez gene record
  51200
• Pubmed identfication
  • 10383164
  • 10860668
• RefSeq identity
  • NM_016352
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000157825
• Locus Specific Databases
  • LRG_1038

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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