CP-466722

Alternative_name

CP-466722; CP466722; CP 466722; 2-(6,7-dimethoxyquinazolin-4-yl)-5-pyridin-2-yl-1,2,4-triazol-3-amine
Description

CP-466722 is a selective inhibitor of ATM kinase with IC50 value of 0.41 μM.
CAS Number

1080622-86-1
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₇H₁₅N₇O₂
Molecular Weight

349.35
Cell Permeable

Yes
Purity

>98%
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A selective inhibitor of ATM kinase
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD17392566
PubChem CID

44551660
PubChem CID Link
SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)N3C(=NC(=N3)C4=CC=CC=N4)N)OC
InChi

InChI=1S/C17H15N7O2/c1-25-13-7-10-12(8-14(13)26-2)20-9-21-16(10)24-17(18)22-15(23-24)11-5-3-4-6-19-11/h3-9H,1-2H3,(H2,18,22,23)
InChi Key

ILBRKJBKDGCSCB-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes

Identity

HGNC:1366
Gene

ADAMTS13
Long gene name

ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms gene
- C9orf8
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms
- VWFCP
- TTP
- vWF-CP
- FLJ42993
- MGC118899
- MGC118900
- DKFZp434C2322
GenBank acession
- AJ011374
Locus

9q34.2
Discovery year

1999-08-23
Entrez gene record

11093
Pubmed identfication
- 11557746
- 11535495
RefSeq identity
- NM_139025
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
VEGA ID

OTTHUMG00000020876
Locus Specific Databases
- LRG_544