Coelenterazine, native

  • Catalog number
    2536-1000
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one, CLZN
  • Description
    Cell-permeable. Coelenterazine is the luminescent substrate for Renilla luciferase and apoaequorin. When coelenterazine combines with luciferase, oxygen, and calcium ions, it produces oxy-coelenterazine and light. This allows coelenterazine to be used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.
  • CAS Number
    55779-48-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₆H₂₁N₃O₃
  • Molecular Weight
    423.46
  • Cell Permeable
    Yes
  • Purity
    ≥95% by TLC
  • Solubilities
    EtOH or MeOH
  • Handling
    Protect from air and moisture
  • Tag Line
    A luminescent substrate
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00467176
  • PubChem CID
    2830
  • SMILES
    C1=CC=C(C=C1)CC2=C3N=C(C(=O)N3C=C(N2)C4=CC=C(C=C4)O)CC5=CC=C(C=C5)O
  • InChi
    InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
  • InChi Key
    YHIPILPTUVMWQT-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Coelenterazine, native
  • Alternative name
    Coelenterazine, native
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