Clofarabine

  • Catalog number
    2236-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
  • Description
    A purine nucleoside antimetabolite that displays anticancer activity. Clofarabine displays potent inhibitory effects on both ribonucleotide reductase and DNA polymerase. Used in pediatrics to treat a type of blood cancer called acute lymphoblastic leukemia (ALL).
  • CAS Number
    123318-82-1
  • Structure Available
    Yes
  • Molecular Formula
    C₁₀H₁₁ClFN₅O₃
  • Molecular Weight
    303.68
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from light and moisture
  • Tag Line
    A purine nucleoside antimetabolite
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00871077
  • PubChem CID
    119182
  • SMILES
    C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(N=C2N)Cl
  • InChi
    InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1
  • InChi Key
    WDDPHFBMKLOVOX-AYQXTPAHSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Clofarabine
  • Alternative name
    Clofarabine
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