Clofarabine
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Catalog number2236-5
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PricePlease ask
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Size5 mg
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Alternative_name(2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
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DescriptionA purine nucleoside antimetabolite that displays anticancer activity. Clofarabine displays potent inhibitory effects on both ribonucleotide reductase and DNA polymerase. Used in pediatrics to treat a type of blood cancer called acute lymphoblastic leukemia (ALL).
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CAS Number123318-82-1
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Structure AvailableYes
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Molecular FormulaC₁₀H₁₁ClFN₅O₃
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Molecular Weight303.68
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Cell PermeableYes
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Purity≥99% by HPLC
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SolubilitiesDMSO
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HandlingProtect from light and moisture
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Tag LineA purine nucleoside antimetabolite
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00871077
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PubChem CID119182
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SMILESC1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(N=C2N)Cl
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InChiInChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1
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InChi KeyWDDPHFBMKLOVOX-AYQXTPAHSA-N
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MSDS AvailableYes
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Gene target
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Short nameClofarabine
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Alternative nameClofarabine
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