p63 Antibody

• Catalog number
  PA2056
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  p63
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB,IHC-P,ICC
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human p63(664-680aa DMDARRNKQQRIKEEGE), different from the related rat and mouse sequences by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the p63 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The p63 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  TP63(Tumor Protein p63), also known as KET, is a protein that in humans is encoded by the TP63 gene. Yang et al.(1998) described the cloning of tumor protein p63, which shows strong homology to the tumor suppressor p53 and the p53-related protein p73. By fluorescence in situ hybridization, Yang et al.(1998) localized the human TP63 gene to chromosome 3q27-q29. Hibi et al.(2000) stated that p53 homologs known variously as p40, p51, p63, and p73L(Trink et al., 1998, Yang et al., 1998, Osada et al., 1998, Senoo et al., 1998) are isoforms of the same gene, which Hibi et al.(2000) referred to as AIS for amplified in squamous cell carcinoma.
• Related articles
  1. Hibi, K., Trink, B., Patturajan, M., Westra, W. H., Caballero, O. L., Hill, D. E., Ratovitski, E. A., Jen, J., Sidransky, D. AIS is an oncogene amplified in squamous cell carcinoma. Proc. Nat. Acad. Sci. 97: 5462-5467, 2000. 2. Osada, M., Ohba, M., Kawahara, C., Ishioka, C., Kanamaru, R., Katoh, I., Ikawa, Y., Nimura, Y., Nakagawara, A., Obinata, M., Ikawa, S. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nature Med. 4: 839-843, 1998. 3. Senoo, M., Seki, N., Ohira, M., Sugano, S., Watanabe, M., Inuzuka, S., Okamoto, T., Tachibana, M., Tanaka, T., Shinkai, Y., Kato, H. A second p53-related protein, p73L, with high homology to p73. Biochem. Biophys. Res. Commun. 248: 603-607, 1998. Note: Erratum: Biochem. Biophys. Res. Commun. 250: 536 only, 1998. 4. Trink, B., Okami, K., Wu, L., Sriuranpong, V., Jen, J., Sidransky, D. A new human p53 homologue. (Letter) Nature Med. 4: 747-748, 1998. 5. Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dotsch, V., Andrews, N. C., Caput, D., McKeon, F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Molec. Cell 2: 305-316, 1998.
• Gene Name
  TP63
• Protein Name
  Tumor protein 63
• Gene Full Name
  tumor protein p63
• Synonyms
  AIS antibody|Amplified in squamous cell carcinoma antibody|B(p51A) antibody|B(p51B) antibody|Chronic ulcerative stomatitis protein antibody|CUSP antibody|DN p63 alpha 1 antibody|DNp63 antibody|EEC3 antibody|id:ibd3516 antibody|Keratinocyte transcription factor antibody|Keratinocyte transcription factor KET antibody|KET antibody|LMS antibody|MGC115972 antibody|MGC192897 antibody|NBP antibody|OFC8 antibody|OTTHUMP00000209732 antibody|OTTHUMP00000209733 antibody|OTTHUMP00000209734 antibody|OTTHUMP00000209735 antibody|OTTHUMP00000209737 antibody|OTTHUMP00000209738 antibody|OTTHUMP00000209739 antibody|OTTHUMP00000209740 antibody|OTTHUMP00000209741 antibody|OTTHUMP00000209742 antibody|OTTHUMP00000209743 antibody|OTTHUMP00000209744 antibody|p40 antibody|p51 antibody|P51/P63 antibody|p53 like transcription factor antibody|p53 related protein antibody|p53-related protein p63 antibody|p53CP antibody|p63 antibody|P63_HUMAN antibody|P73 antibody|p73H antibody|p73L antibody|RHS antibody|SHFM4 antibody|TAp63alpha antibody|TP53CP antibody|TP53L antibody|TP63 antibody|TP73 antibody|TP73L antibody|Transformation related protein 63 antibody|Transformation-related protein 63 antibody|Trp53rp1 antibody|Trp63 antibody|Tumor protein 63 antibody|tumor protein 63 kDa with strong homology to p53 antibody|Tumor protein p53-competing protein antibody|Tumor protein p53-like antibody|tumor protein p63 antibody|Tumor protein p63 deltaN isoform delta antibody|Tumor protein p73 antibody|tumor protein p73-like antibody
• Uniprot ID
  Q9H3D4
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p63  
• Gene symbol
  TPRG1LP1, CKAP4, TP63
• Short name
  p63 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  p63 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:52353
• Gene
  TPRG1LP1
• Long gene name
  tumor protein p63 regulated 1 like pseudogene 1
• Locus
  19q13.43
• Discovery year
  2016-07-28
• Entrez gene record
  100130490
• VEGA ID
  OTTHUMG00000183473

Gene info

• Identity
  HGNC:16991
• Gene
  CKAP4
• Long gene name
  cytoskeleton associated protein 4
• Synonyms gene name
  • cytoskeleton-associated protein 4
• Synonyms
  • P63
  • CLIMP-63
  • ERGIC-63
• GenBank acession
  • X69910
• Locus
  12q23.3
• Discovery year
  2001-11-14
• Entrez gene record
  10970
• Pubmed identfication
  • 8314870
• VEGA ID
  OTTHUMG00000170085

Gene info

• Identity
  HGNC:15979
• Gene
  TP63
• Long gene name
  tumor protein p63
• Synonyms gene
  • TP73L
  • TP53L
  • TP53CP
• Synonyms gene name
  • tumor protein p73-like
  • tumor protein p53-like
  • tumor protein p53-competing protein
• Synonyms
  • p51
  • SHFM4
  • EEC3
  • p63
  • p73L
  • OFC8
  • KET
  • p73H
  • NBP
  • p53CP
• GenBank acession
  • AB010153
• Locus
  3q28
• Discovery year
  2002-04-18
• Entrez gene record
  8626
• Pubmed identfication
  • 9774969
  • 9662378
  • 11181441
  • 11181451
• RefSeq identity
  • NM_003722
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156313
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_428

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products