CK8 (Ser24) Antibody

• Catalog number
  bs-3743R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CK8 (Ser24) Primary Polyclonal Antibody
• Also known as
  CK8 (Ser24) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CK8 Ser24
• Specificity
  This is a highly specific antibody against CK8 Ser24.
• Modification s
  Phosphorylation
• Modification site s
  Ser24
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser24
• Gene ID number
  3856
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8; KRT8; CYK8
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CK8   Ser24  
• Gene symbol
  KRT8
• Short name
  Anti-CK8 Ser24
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CK8 (Ser24) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6446
• Gene
  KRT8
• Long gene name
  keratin 8
• Synonyms gene name
  • keratin 8, type II
• Synonyms
  • CARD2
  • K8
  • CK8
  • CYK8
  • K2C8
  • KO
• GenBank acession
  • BC000654
• Locus
  12q13.13
• Discovery year
  1988-08-12
• Entrez gene record
  3856
• Pubmed identfication
  • 2434381
  • 1705144
  • 16831889
• RefSeq identity
  • NM_002273
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169881

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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