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Target antigen
cIAP2
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
mouse
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Analyses
WB
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Immunogen
E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the cIAP2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The cIAP2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
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Related articles
1. "Entrez Gene: BIRC3 baculoviral IAP repeat-containing 3". 2. Liston P, Roy N, Tamai K, Lefebvre C, Baird S, Cherton-Horvat G, Farahani R, McLean M, Ikeda JE, MacKenzie A, Korneluk RG (February 1996). "Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes". Nature 379 (6563): 349–53. 3. Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV (February 1996). "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins". Cell 83 (7): 1243–52.
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Gene Name
BIRC3
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Protein Name
Baculoviral IAP repeat-containing protein 3
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Gene Full Name
baculoviral IAP repeat containing 3
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Synonyms
AIP 1 antibody|AIP1 antibody|API 2 antibody|API2 antibody|API2 antibody|Apoptosis inhibitor 2 antibody|Baculoviral IAP repeat containing 3 antibody|Baculoviral IAP repeat containing protein 3 antibody|Baculoviral IAP repeat-containing protein 3 antibody|BIRC 3 antibody| BIRC3 antibody|BIRC3 antibody|BIRC3_HUMAN antibody|C IAP2 antibody|C-IAP2 antibody|CIAP 2 antibody|CIAP 2 antibody|CIAP2 antibody|HAIP 1 antibody|HAIP1 antibody|HAIP1 antibody|HIAP 1 antibody|HIAP-1 antibody|HIAP1 antibody|IAP homolog C antibody|IAP-1 antibody|Inhibitor of apoptosis protein 1 antibody|Inhibitor of apoptosis protein 1 antibody|MALT 2 antibody| MALT2 antibody|Mammalian IAP homolog C antibody|MIHC antibody|MIHC antibody|RING finger protein 49 antibody|RNF49 antibody|TNFR2 TRAF signaling complex protein 1 antibody|TNFR2 TRAF signalling complex protein antibody|TNFR2-TRAF-signaling complex protein 1 antibody
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Uniprot ID
Q13489
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Entrez GeneID
330
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
