Chondroitin sulfate proteoglycan NG2 Antibody

• Catalog number
  bs-4800R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Chondroitin sulfate proteoglycan NG2 Antibody
• Also known as
  Chondroitin sulfate proteoglycan NG2 Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Chondroitin sulfate proteoglycan NG2
• Specificity
  This is a highly specific antibody against Chondroitin sulfate proteoglycan NG2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  730-780/2322
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chondroitin sulfate proteoglycan NG2
• Gene ID number
  1464
• Swiss Prot
  Q6UVK1
• Tested Applications
  FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NG2; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG; Chondroitin sulfate proteoglycan 4; Chondroitin sulfate proteoglycan NG2; Melanoma chondroitin sulfate proteoglycan; Melanoma-associated chondroitin sulfate proteoglycan; CSPG4
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Chondroitin   sulfate   proteoglycan   NG2  
• Gene symbol
  NPM1P2, RNF5, CSPG4
• Short name
  Anti-Chondroitin sulfate proteoglycan NG2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Chondroitin sulfate proteoglycan NG2 Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7922
• Gene
  NPM1P2
• Long gene name
  nucleophosmin 1 pseudogene 2
• Synonyms gene
  • NPMP2
• Synonyms gene name
  • nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 2
• Synonyms
  • NG2-6
• GenBank acession
  • X54171
• Locus
  18q11.2
• Discovery year
  1993-08-24
• Entrez gene record
  4871
• Pubmed identfication
  • 8471164
  • 2157848
• VEGA ID
  OTTHUMG00000179428

Gene info

• Identity
  HGNC:10068
• Gene
  RNF5
• Long gene name
  ring finger protein 5
• Synonyms gene name
  • ring finger protein 5, E3 ubiquitin protein ligase
• Synonyms
  • NG2
  • G16
  • RING5
  • RMA1
• GenBank acession
  • U89336
• Locus
  6p21.32
• Discovery year
  1997-10-16
• Entrez gene record
  6048
• Pubmed identfication
  • 9533025
• RefSeq identity
  • NM_006913
• Classification
  • MicroRNA protein coding host genes
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000031093

Gene info

• Identity
  HGNC:2466
• Gene
  CSPG4
• Long gene name
  chondroitin sulfate proteoglycan 4
• Synonyms gene name
  • chondroitin sulfate proteoglycan 4 (melanoma-associated)
• Synonyms
  • MCSPG
  • MEL-CSPG
  • MSK16
  • NG2
  • MCSP
  • HMW-MAA
  • CSPG4A
• Synonyms name
  • melanoma-associated chondroitin sulfate proteoglycan
• GenBank acession
  • X96753
  • AY359468
• Locus
  15q24.2
• Discovery year
  1997-11-28
• Entrez gene record
  1464
• Pubmed identfication
  • 8790396
  • 16407841
• RefSeq identity
  • NM_001897
• Classification
  • Proteoglycans
• VEGA ID
  OTTHUMG00000142836

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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