CHAC1 Polyclonal Antibody

CHAC1 Polyclonal Antibody is available 2 times from Bioma labs

CAC07471 | CHAC1 Polyclonal Antibodysize: 50 μg | 285.92 USD

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CAC07471 | CHAC1 Polyclonal Antibodysize: 100 μg | 467.97 USD

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  • Other name
    Glutathione-specific gamma-glutamylcyclotransferase 11 Publication,CHAC11,Blocks Notch protein1
  • Immunogen
    Recombinant human Glutathione-specific gamma-glutamylcyclotransferase 1 protein (43-264AA)
  • Verified reactivity
    Human, Mouse
  • Verified applications
    ELISA,WB,IHC. Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
  • Raised in
    Rabbit
  • Clonality
    Polyclonal
  • Protein number
    Q9BUX1
  • Gene number
    Please refer to GenBank
  • NCBI number
    Please refer to NCBI
  • Purity
    Caprylic Acid Ammonium Sulfate Precipitation Purified
  • Storage recommendation
    Aliquot and store at -20°C. Minimize freezing and thawing.
  • Use before
    1 year
  • Shipping requirements
    Blue ice
  • Estimated production time
    3-7 business days
  • Supplementary information
    Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution (PubMed:23070364). Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
  • Notes
    For research use only. Not for diagnostic procedures.
  • Properties
    If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • French translation
    anticorps
  • Gene target
  • Short name
    CHAC1 Polyclonal Antibody
  • Technique
    Polyclonal, Antibody
  • Alternative name
    ChaC, cation transport regulator homolog 1 (E. coli) polyclonal (Antibody to)
  • Alternative technique
    polyclonals
  • Alternative to gene target
    ChaC, cation transport regulator homolog 1 (E. coli), CHAC1 and IDBG-6874 and ENSG00000128965 and 79094, protein binding, Cytoplasm, Chac1 and IDBG-199330 and ENSMUSG00000027313 and 69065, CHAC1 and IDBG-646277 and ENSBTAG00000010371 and 505991
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